1887
Volume 2 (2021) Number 2
  • EISSN: 2708-0463

Abstract

تهدف هذه الدراسة إلى تقييم مدى فاعلية وتأثير بعض المطهرات والمعقمات المستخدمة في المرافق الصحية، وخصوصًا في مستشفى مصراتة المركزي، بحسب التراكيز المعدّة لهذه المرافق، على مجموعة البكتيريا الزائفة () المعزولة من قسم الولادة ووحدة العناية المركّزة للأطفال حديثي الولادة بمستشفى مصراتة المركزي، في الفترة من 11 أكتوبر2017 إلى 8 مارس 2018، مع العامل الزمني لهذا التأثير، حيث كانت الأنواع المعزولة هي ()، ()، ()، ()، ()، (). وباستخدام أقراص ورق الترشيح المشبعة بالمعقم (Disk diffusion)، وكانت المعقمات والمطهرات، هي: (Ethanol)، (NaClO)، (Propanol AF)، (Desreson AF)، (Cidex)، (Decosept)، (Minuson AF)، (Dettol)، أظهرت النتائج تأخرًا في تأثير هذه المعقمات؛ إذ لم يظهر أي تأثير قبل 20 دقيقة من التعريض، وكان أكثرها فاعلية مطهر (Cidex) عند 20 دقيقة ضد الأنواع الثلاثة () و() و()، ثم بعد 24 ساعة لوحظت فاعلية جيدة على أغلب الأنواع للمعقمات (Decosept) و(NaClO) و(Dettol) و(Derseson)، ولكن ليس على كل الأنواع، مع فاعلية جيدة لمعقم (Propanol) على كل الأنواع، وتأثير خفيف لمطهر (Ethanol) ابتداء من الدقيقة 20، وانعدام أي تأثير لمعقم (Minuson) على هذه الأنواع، حيث تراوح حجم الهالة على هذه البكتيريا من 3 مليمترات إلى 2.5 سنتيمتر.

This study aimed to evaluate the effectiveness and impact of some disinfectants and sterilizers used at health facilities, especially in Misurata Central Hospital, Libya. The study examined the concentrations prepared for usage at these facilities and the time factor of their effectiveness on a group of Pseudomonas bacteria isolated from the Maternity Department and the Neonatal Intensive Care Unit in this Hospital (11 October 2017 to 8 March 2018). The isolated bacteria species were: , , , , , . The study used disinfectants impregnated with filter paper discs (disk diffusion). The disinfectants used were: Ethanol, NaClO, Propanol AF, Desreson AF, Cidex, Decosept, Minuson AF and Dettol. : The results showed a delay in the effectiveness of these sterilizers. None of them showed any effect during the first 20 minutes of exposure. The most impactful disinfectant at 20 minutes was Cidex against the three types of bacteria: , , and . Twenty four hours later, good efficacy was observed for most of the sterilizers such as Decosept, NaClO, Dettol and Desreson AF, but not on all types of bacteria. Propanol AF sterilizer showed good efficacy on all species, while Ethanol showed slight results starting from minute 20. However, Minuson sterilizer showed no effects on these species. The diameter of the inhibition area on these types of bacteria ranged from 3 mm to 2.5 cm.

Loading

Article metrics loading...

/content/journals/10.5339/ajsr.2021.11
2021-10-31
2024-11-09
Loading full text...

Full text loading...

/deliver/fulltext/ajsr/2021/2/ajsr.2021.11.html?itemId=/content/journals/10.5339/ajsr.2021.11&mimeType=html&fmt=ahah

References

  1. Quinn MM, Henneberger PK, Braun B, Delclos GL, Fagan K, Huang V, et al. Cleaning and disinfecting environmental surfaces in health care: Toward an integrated framework for infection and occupational illness prevention. American Journal of Infection Control. 2015;43(5):424‒434.
  2. Al-Tawfiq JA, Tambyah PA. Healthcare associated infections (HAI) perspectives. Journal of Infection and Public Health. 2014;7:339–344.
  3. World Health Organization. Global Guidelines for the Prevention of Surgical Site Infection; 2016. Available from: http://www.who.int/about/licensing/copyright_form.
  4. Hota B. Contamination, Disinfection and Cross-Colonization: Are Hospital Surfaces Reservoirs for Nosocomial Infection?. Health Care Epidemiology, Clinical Infectious Diseases, 2004 Oct 15;39(8):1182-9.
  5. Polin RA and Saiman L. Nosocomial infections in the neonatal intensive care unit, NeoReviews, An official Journal of the American Academy of Pediatrics, 2003;4(3):e81–e89.
  6. Dennis R, David H, Robert P. Major trends in the microbial etiology of nosocomial infection. USA: Elsevier; 2017.
  7. Cross A, Allen JR, Burke J, Ducel G, Harris A, John J, Johnson D, Lew M, MacMillan B, Meers P, Skalova R, Wenzel R and Tenney J. Nosocomial infection due to Pseudomonas aeruginosa: Review of recent trends. Reviews of Infectious Diseases. JSTOR, Published By: Oxford University Press, 1983;5(5):S837–S845 (9 pages). https://www.jstor.org/stable/4453236
  8. Ahmed BM, Wafaa AZ, Ghada RH, Aza ZL, Rasha G. Prevalence of Multidrug-Resistant Pseudomonas aeruginosa in Patients with Nosocomial Infections at a University Hospital in Egypt, with Special Reference to Typing Methods. IBIMA Publishing, Journal of Virology & Microbiology, Vol. 2013 (2013), Article ID 290047, 13 pages.
  9. Michael JR, Jonathan RE, David HC, Robert P. Nosocomial infection in pediatric intensive care units in the United States. American Academy of Pediatrics. 1999;103(4); e39. DOI: http://pediatrics.aappublications.org/content/103/4/e39
  10. Isles A, Maclusky I, Corey M, Gold R, Prober C. Pseudomonas cepacia infection in cystic fibrosis: An emerging problem. Journal of Pediatrics. 1984;104(2):206–210.
  11. Public Health Agency of Canada. Pathogen Safety Data Sheets: Infectious Substances – Pseudomonas spp. 2011. https://www.canada.ca/en/public-health/services/laboratory-biosafety-biosecurity/pathogen-safety-data-sheets-risk-assessment/pseudomonas.html
  12. Ali F, Maryam E. The disinfectant effects of benzalkonium chloride on some important foodborne pathogens. American-Eurasian Journal of Agricultural & Environmental Sciences. 2012;12(1):23–29.
  13. European Centre for Disease Prevention and Control (ECDC); 2019 [accessed 2019 January 23]. PIIS, 1473-3099(18)30605-4.
  14. Italian Prevalence Study on Infections Related to the Assistance and Use of Antibiotics in Acute Care Hospitals—ECDC Protocol, Italian Report PPS2, 2017; p. 2.
  15. A Centers for Disease Control and Prevention. Guidance document Disinfection and sterilization in healthcare facilities; 2008.
  16. Larson EL, Morton HE. Alcohols. In: Block, S.S., Ed., Disinfection, Sterilization, and Preservation, 4th Edition, Lea and Febiger, Philadelphia, 1991. pA: 191–203.
  17. Raut G, Vanmali H, Pimpliskar M, Rahul J. Efficacy of some antiseptics and disinfectants: A review. International Journal of Pharmacy & Pharmaceutical Research [Internet]. 2015;4(4):182–197. Available from: www.ijppr.humanjournals.com.
  18. Divya G, Vinoth kumar S, Sankar VA, Kirthika M. Detection of the most effective disinfectant against MDR bacteria in hospital infections. International Journal of Biology, Pharmacy and Allied Sciences, (IJBPAS), April, 2015, 4(4): 1939-1999.
  19. Russell AD. Activity of biocides against mycobacteria. Journal of Applied Bacteriology Symposium Supplement. 1996;81:87–101.
  20. Paul M, Shani V, Mucihtar E, Kariv G, Robenshtok E, Leibovici L. Systematic review and meta-analysis of the efficacy of appropriate empiric antibiotic therapy for sepsis. Antimicrobial Agents and Chemotherapy. 2010;54:4851–4863.
  21. Laxminarayan R, Duse A, Wattal C, Zaidi AK, Wertheim HF, Sumpradit N, et al. Antibiotic resistance—the need for global solutions. Lancet Infectious Diseases. 2013;13:1057–1098.
  22. West AM, Teska PJ, Lineback CB, Oliver HF. Strain, disinfectant, concentration, and contact time quantitatively impact disinfectant efficacy. Antimicrobial Resistance and Infection Control. 2018;7:49.
  23. Wladyslaw JK. Hospital acquired infections: The epidemiology and aerobiological pathways of air borne Nosocomial infection and methods of air and surface disinfection. New York, USA: Penton Media; 2007.
  24. Akolaibe AM, Al-Ameri GA, Alkadasi MN. Study of the efficacy of disinfectant against bacterial contamination in burns unit algumhory and International Yemen Hospitals in Taiz City. International Journal of Research Studies in Biosciences (IJRSB). March 2015;3(3):26–33.
  25. Cordoba LK, Mosquera LL, Tarazona-Diaz GP, Arias-Palacios JD. Evaluation of the efficacy of a hydrogen peroxide disinfectant. International Journal of Pharmacy and Pharmaceutical Sciences. 2018;10(10):104–108.
  26. Mete A. Antibacterial efficacy of some antiseptics and disinfectants against common bacterial agents isolated from horses in Turkey. Acta Veterinaria Eurasia. 2019;45:101–107.
  27. Al-Talib H, Alkhateeb A, Ruzuki A, Zulkifil N, Hamizi S, Muhammad N, et al. Effectiveness of commonly used antiseptics on bacteria causing nosocomial infections in tertiary hospital in Malaysia. African Journal of Microbiology Research. 2019;13(10):188–194.
  28. Keah KC, Jegathesan M, Tan SC, Chan SH, Chee OM, Cheong YM, Suleiman AB. Bacterial contamination of hospital disinfectants. Medical Journal Malaysia. 1995 Dec;50(4): 291-7.
/content/journals/10.5339/ajsr.2021.11
Loading
/content/journals/10.5339/ajsr.2021.11
Loading

Data & Media loading...

This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error