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Volume 2023, Issue 4
  • ISSN: 1999-7086
  • EISSN: 1999-7094

Abstract

The coronavirus disease (COVID-19) has resulted in more than 6 million deaths worldwide since it was identified in 2019, resulting in significant morbidity and mortality. The impact of COVID-19 on the acquisition of multi-drug-resistant organisms (MDRO) remains uncertain. This study aims to investigate the effect of COVID-19 on the acquisition of MDRO in the intensive care unit (ICU).

A single-center, retrospective observational study at Wollongong ICU compared the acquisition rate of MDRO, especially vancomycin-resistant enterococci (VRE) and methicillin-resistant (MRSA), pre- and post-COVID.

There was a significant increase in MDRO incidence post-COVID compared to pre-COVID, with incidence rates increasing from 1.6% to 4.56%, especially in MRSA acquisitions, which increased from 0.91% to 5.71%. This increase was associated with a longer ICU length of stay (LOS) but did not have a significant effect on hospital LOS or mortality. The increased incidence of MDRO was potentially related to increased antibiotic use and staffing changes during the COVID period.

COVID-19 significantly impacted the acquisition of MDRO, particularly MRSA.

© 2023 Abdelhamid, Jagarlamudi, Abdelwahed, licensee HBKU Press.
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2023-11-01
2024-07-04
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/content/journals/10.5339/jemtac.2023.33
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Impact of COVID-19 on acquisitions of multi-drug-resistant organisms in a tertiary intensive care unit: A single center retrospective observational study
Journal of Emergency Medicine, Trauma and Acute Care 2023, 33 (2023); https://doi.org/10.5339/jemtac.2023.33
/content/journals/10.5339/jemtac.2023.33
/content/journals/10.5339/jemtac.2023.33
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Keyword(s): Coronavirus disease, intensive care unit, methicillin-resistant Staphylococcus aureus, multi-drug-resistant organisms and vancomycin-resistant enterococci

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