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6 - Al-Bayan University Scientific Conference
  • ISSN: 1999-7086
  • EISSN: 1999-7094

Abstract

Asthma is a widespread respiratory illness that affects millions of people worldwide, including pregnant women. Using spirometry testing, this study examines the effects of pregnancy on the lungs of pregnant women with and without bronchial asthma. The survey included 200 asthmatic pregnant women overall and 100 pregnant healthy women. FEV1, PEFR, FVC, and FEV1/FVC ratio, among other lung function indicators, were measured during the second and third trimesters of pregnancy. The findings show that pregnant women with asthma have significantly worse lung function than healthy pregnant women, with lower FEV1, PEFR, and FEV1% values. In addition, changes in lung function and body mass index (BMI) were observed between the second and third trimesters. The FEV1/FVC ratio remained largely stable, although both FVC and FEV1% decreased significantly. These results highlight the dynamic nature of lung function and BMI during pregnancy and also highlight the importance of monitoring these changes for the health of expectant mothers and their unborn children. To ensure maternal and fetal health, it is essential to understand these physiological changes, especially in people with asthma. Future evaluation of spirometry data should consider reference equations tailored to pregnant women. This will provide important insights into the complex relationship between respiratory health and pregnancy.

© 2024 Al-Shamma, Alkhafaji, Al-Hindy, licensee HBKU Press.
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2024-10-10
2024-12-05
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References

  1. García-Marcos L, Chiang C-Y, Asher MI, Marks GB, El Sony A, Masekela R, et al. Asthma management and control in children, adolescents, and adults in 25 countries: A Global Asthma Network Phase I cross-sectional study. Lancet Glob Health. 2023; 11:(2):E218ȓ28. doi: 10.1016/S2214-109X(22)00506-X.
     [Google Scholar]
  2. Wong QYA, Lim JJ, Ng JY, Malipeddi P, Lim YYE, Sio YY, et al. An updated prevalence of asthma, its phenotypes, and the identification of the potential asthma risk factors among young Chinese adults recruited in Singapore. World Allergy Organ J. 2023; 16:(3):100757. doi: 10.1016/j.waojou.2023.100757. PubMed PMID: 36968625; PubMed Central PMCID: PMCPMC10033744.
     [Google Scholar]
  3. Al-Hindy HA-AM, Al-Athari AJH, Mousa MJ, Hameed SJ, Obeed SH. The utility of serum IL-1β and CRP together with fractional exhaled nitric oxide in the diagnosis of asthma in adults. NeuroQuantology. 2021; 19:(8):119ȓ124. doi: 10.14704/nq.2021.19.8.NQ21122.
     [Google Scholar]
  4. Alzughaibi MA, Abdalhadi NA, Shumran AM, Al-Hindy HA-AM, Al-Dahmoshi HOM, Al-Khafaji NSK, et al. The association of serum 1, 25-dihydroxy vitamin D2 status with asthma in a comparative study of Iraqi adults. Biochem Cell Arch. 2022; 22:(1):1267ȓ72.
     [Google Scholar]
  5. Ruhighira JJ, Mashili FL, Tungu AM, Mamuya S. Spirometry profiles among pregnant and non-pregnant African women: A cross-sectional study. BMC Womens Health. 2022; 22:(1):483. doi: 10.1186/s12905-022-02081-6.
     [Google Scholar]
  6. Amjed HA, Abdul-Amir A-H, Shahlaa Kh C, Mazin JM. Conicity index as an anthropometric index of central obesity in the prediction of adult bronchial asthma; correlation with fractional exhaled nitrous oxide tests. Medico Legal Update. 2021; 21:(2):1467ȓ73. doi: 10.37506/mlu.v21i2.2901.
     [Google Scholar]
  7. Abbas AH, Khadim HW, Jasim AH, Al-Hindy, HA-AM, Hammoud SS, . Early detection and diagnosis of chronic obstructive pulmonary disease in asymptomatic male smokers and ex-smokers using spirometry. Rev Latinoam Hipertens. 2021; 16:(1):44ȓ50. doi: 10.5281/zenodo.5106415.
     [Google Scholar]
  8. Alkhazraji EK, Alkhafaji AA, Alzughaibi MA, Alhindy HA-A, Mousa MJ. Positive correlation of circulating tumor necrosis factor-alpha (TNFα) with spirometric pulmonary tests in adult asthmatic patients. Biochem. Cell. Arch. 2021; 21:(Supplement 1):2605–10.
     [Google Scholar]
  9. Abbas AH, Rasheed MA, Al-Hindy HA-A, Mousa MJ, Al-Shalah HAA. The role of serum IL-1β in combination with fractional exhaled nitric oxide in the diagnosis of adult bronchial asthma. NeuroQuantology. 2021; 19:(8):13ȓ9. doi: 10.14704/nq.2021.19.8.NQ21107.
     [Google Scholar]
  10. AL-Daami QJ, Bash HS, Naji GH, AL-Hindy HA-AM. High-sensitivity C – reactive protein assessment in bronchial asthma: Impact of exhaled nitric oxide and body mass index. Syst Rev. Pharm. 2020; 11:(3):705ȓ11. doi: 10.31838/srp.2020.3.96.
     [Google Scholar]
  11. Ruhighira JJ, Mashili FL, Tungu AM, Kibusi S. Spirometry performance quality and lung function pattern during pregnancy; should testing conditions and interpretation criteria be re-evaluated? MedRxiv. 2023:23290897. doi: 10.1101/2023.06.02.23290897.
     [Google Scholar]
  12. Wang H, Li N, Huang H. Asthma in pregnancy: Pathophysiology, diagnosis, whole-course management, and medication safety. Can Respir J. 2020;2020:9046842. doi: 10.1155/2020/9046842. PubMed PMID: 32184907; PubMed Central PMCID: PMCPMC7060439.
     [Google Scholar]
  13. Chaplin S. Summary of ERS/ATS guideline on managing severe asthma. Guidelines 2020; 31:(10):27–31. doi: 10.1002/psb.1872.
     [Google Scholar]
  14. Johnson JD, Theurer WM. A stepwise approach to the interpretation of pulmonary function tests. Am Fam Physician. 2014; 89:(5):359ȓ66.
     [Google Scholar]
  15. Ponce MC, Sankari A, Sharma S. Pulmonary function tests. In: StatPearls [Internet] Treasure island (FL). StatPearls Publishing. 2024 Jan. https://www.ncbi.nlm.nih.gov/books/NBK482339/.
     [Google Scholar]
  16. Vestbo J, Hurd SS, Agustí AG, Jones PW, Vogelmeier C, Anzueto A, et al. Global strategy for the diagnosis, management, and prevention of chronic obstructive pulmonary disease: GOLD executive summary. Am J Respir Crit Care Med. 2013; 187:(4):347ȓ65. doi: 10.1164/rccm.201204-0596PP. PubMed PMID: 22878278.
     [Google Scholar]
  17. Program NAEaP. Expert Panel Report 3 (EPR-3): Guidelines for the diagnosis and management of asthma-summary report 2007. J Allergy Clin Immunol. 2007; 120:(5 Suppl):S94–138. doi: 10.1016/j.jaci.2007.09.043. PubMed PMID: 17983880.
     [Google Scholar]
  18. LoMauro A, Aliverti A. Respiratory physiology of pregnancy. Physiology masterclass. Breathe (Sheff). 2015; 11:(4):297ȓ301. doi: 10.1183/20734735.008615.
     [Google Scholar]
  19. Kominiarek MA, Peaceman AM. Gestational weight gain. Am J Obstet Gynecol. 2017; 217:(6):642ȓ51. doi: 10.1016/j.ajog.2017.05.040. PubMed PMID: 28549978; PubMed Central PMCID: PMCPMC5701873.
     [Google Scholar]
  20. Abd Al-Abbass HA, Fadhil Obaid A, Al-Hindy HA-AM, Abdulrasol ZA, Shlash AMJ. Epidemiological characteristics and disease complications in thalassemia syndrome patients in Babylon, Iraq. J Babol Univ Med Sci. 2024;26:e22.
     [Google Scholar]
  21. Al Sa'ady AT, Abdulrasol ZAA, Obaid AF, Alhindy HA-AM, Al-Mumin AS. Prevalence of adverse effects from COVID-19 vaccine among Iraqi adults: A retrospective cross-sectional study. J Emerg Med Trauma Acute Care. 2022; 2022:(3):1ȓ9. doi: 10.5339/jemtac.2022.ismc.6.
     [Google Scholar]
  22. Hamann V, Deruelle P, Enaux C, Deguen S, Kihal-Talantikite W. Physical activity and gestational weight gain: A systematic review of observational studies. BMC Public Health. 2022; 22:(1):1951. doi: 10.1186/s12889-022-14324-0.
     [Google Scholar]
  23. Abdul-Husseein HK, Al-Akkam KA, Abdul-Husseein MK, Al-Hindy HA-AM. Liver function abnormalities in COVID-19 patients and their association with age and sex: A cross-sectional study. Arch Razi Inst. 2023; 78:(1):453ȓ8. doi: 10.22092/ARI.2022.359755.2474. PubMed Central PMCID: PMCPMC10258244.
     [Google Scholar]
  24. Mehta UJ, Siega-Riz AM, Herring AH. Effect of body image on pregnancy weight gain. Matern Child Health J. 2011; 15:(3):324ȓ32. doi: 10.1007/s10995-010-0578-7. PubMed PMID: 20204481; PubMed Central PMCID: PMCPMC3665282.
     [Google Scholar]
  25. Status IoMSoN, Pregnancy WGd, Intake IoMSoD, Pregnancy NSd. Nutrition during pregnancy: Part I: weight gain, Part II: nutrient supplements. National Academies Press. 1990. doi: 10.17226/1451.
  26. Maisonneuve E, Rey E. Obésité et grossesse: revue des risques et de la prise en charge obstétricale. Rev Méd Périnat. 2011;3:11–8. doi: 10.1007/s12611-011-0100-5.
     [Google Scholar]
  27. LoMauro A, Aliverti A, Frykholm P, Alberico D, Persico N, Boschetti G, et al. Adaptation of lung, chest wall, and respiratory muscles during pregnancy: preparing for birth. J Appl Physiol. 2019; 127:(6):1640ȓ50. doi: 10.1152/japplphysiol.00035.2019. PubMed PMID: 31697596.
     [Google Scholar]
  28. Contreras G, Gutiérrez M, Beroíza T, Fantín A, Oddó H, Villarroel L, et al. Ventilatory drive and respiratory muscle function in pregnancy. Am Rev Respir Dis. 1991; 144:(4):837ȓ41. doi: 10.1164/ajrccm/144.4.837. PubMed PMID: 1928958.
     [Google Scholar]
  29. Field SK, Bell SG, Cenaiko DF, Whitelaw WA. Relationship between inspiratory effort and breathlessness in pregnancy. J Appl Physiol. 1991; 71:(5):1897ȓ902. doi: 10.1152/jappl.1991.71.5.1897.
     [Google Scholar]
  30. Grindheim G, Toska K, Estensen M-E, Rosseland LA. Changes in pulmonary function during pregnancy: A longitudinal cohort study. BJOG. 2012; 119:(1):94ȓ101. doi: 10.1111/j.1471-0528.2011.03158.x. PubMed PMID: 22004272.
     [Google Scholar]
  31. Jensen D, Webb KA, Davies GA, O'Donnell DE. Mechanical ventilatory constraints during incremental cycle exercise in human pregnancy: Implications for respiratory sensation. J Physiol. 2008; 586:(Pt 19):4735–50. doi: 10.1113/jphysiol.2008.158154. PubMed PMID: 18687714; PubMed Central PMCID: PMCPMC2614045.
     [Google Scholar]
  32. Kolarzyk E, Szot WM, Lyszczarz J. Lung function and breathing regulation parameters during pregnancy. Arch Gynecol Obstet. 2005; 272:(1):53ȓ8. doi: 10.1007/s00404-004-0691-1. PubMed PMID: 15616844.
     [Google Scholar]
  33. Prevention CfDCa. Spirometry quality assurance: Common errors and their impact on test results; 2014. https://www.cdc.gov/niosh/docs/2012-116/pdfs/2012-116.pdf:1–34 .
  34. Weis CA, Triano JJ, Barrett J, Campbell MD, Croy M, Roeder J. Ultrasound assessment of abdominal muscle thickness in postpartum vs nulliparous women. J Manipulative Physiol Ther. 2015; 38:(5):352ȓ7. doi: 10.1016/j.jmpt.2015.06.005. PubMed PMID: 26189917.
     [Google Scholar]
  35. Puranik BM, Kurhade GA, Kaore SB, Patwardhan SA, Kher JR. PEFR in pregnancy: A longitudinal study. Indian J Physiol Pharmacol. 1995; 39:(2):135ȓ9. PubMed PMID: 7649601.
     [Google Scholar]
  36. LoMauro A, Aliverti A, Alberigo D, Persico N, Frykholm P, Briganti F, et al. The effect of pregnancy on respiratory function. Eur Respir J. 2018;52:OA2149. doi: 10.1183/13993003.congress-2018.OA2149.
     [Google Scholar]
/content/journals/10.5339/jemtac.2024.absc.3
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Analyzing spirometry profile of pulmonary function pattern among gestating women with bronchial asthma: A case–control study
Journal of Emergency Medicine, Trauma and Acute Care 2024, 3 (2024); https://doi.org/10.5339/jemtac.2024.absc.3
/content/journals/10.5339/jemtac.2024.absc.3
/content/journals/10.5339/jemtac.2024.absc.3
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Keyword(s): asthma, FEV, FEV1, FVC, pregnancy and pulmonary function tests,

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