1887
  1. Home
  2. A-Z Publications
  3. Journal of Emergency Medicine, Trauma and Acute Care
  4. Volume 2025, Issue 2
  5. Article
Volume 2025, Issue 2
  • ISSN: 1999-7086
  • EISSN: 1999-7094

Abstract

Considering the aging society, there are few studies on the development of contrast-induced nephropathy (CIN) in emergency departments (EDs), especially in geriatric age groups. The aim of this study was to evaluate the effects of intravenous contrast media use for computed tomography on the development of acute kidney injury (AKI) in geriatric patients admitted to the ED.

This was a single-center, retrospective study. Patients aged ≥65 years presenting to the ED with an indication for contrast-enhanced computed tomography with serum Creatin and urea values within 8 h before imaging and 24–48 h after imaging were included in the study. The contrast agent used was IOHEKSOL (100 ml/300 mg). Patients with elevated serum creatine values 24–48 h after contrast-enhanced computed tomography were considered as contrast-induced acute kidney injury (CI-AKI).

This study included 420 patients. The number of patients who developed CI-AKI was = 35. When the characteristics of the patients were compared according to the development of CI-AKI, significant differences were found in terms of baseline creatinine value, eGFR and all severity indicators of CI-AKI (hypotension, hypoalbuminemia, and intensive care unit admission) ( < 0.05 for all).

Our study showed that the development of CIN in geriatric patients presenting to the ED was the same as in the general population and that the basal urea, sCr, and eGFR values of the patients also influenced the development of CIN. We believe that this study may be useful to know the comorbidities and laboratory values of patients before contrast extraction in order to be prepared for a possible complication.

© 2025 Ertaş, Emektar, Çorbacioğlu, Çevik, licensee HBKU Press.
Loading

Article metrics loading...

/content/journals/10.5339/jemtac.2025.14
2025-04-08
2025-04-16
The full text of this item is not currently available.

References

  1. Guo W, Liu J, He Y, et al. The impact of contrast-associated acute kidney injury on all-cause mortality in older patients after coronary angiography: A 7.5-year follow-up. Angiology. 2024; 75:434–440. https://doi.org/10.1177/00033197231155610
     [Google Scholar]
  2. Bahreini E, Rezaei-Chianeh Y, Nabi-Afjadi M. Molecular mechanisms involved in intrarenal renin-angiotensin and alternative pathways in diabetic nephropathy - a review. Rev Diabet Stud RDS. 2021; 17:1–10. https://doi.org/10.1900/RDS.2021.17.1
     [Google Scholar]
  3. Ramachandran P, Jayakumar D. Contrast-induced acute kidney injury. Indian J Crit Care Med Peer Rev. 2020; 24:S122–S125. https://doi.org/10.5005/jp-journals-10071-23379
     [Google Scholar]
  4. Lakhal K, Ehrmann S, Robert-Edan V. Iodinated contrast medium: Is there a re(n)al problem? A clinical vignette-based review. Crit Care. 2020; 24:641. https://doi.org/10.1186/s13054-020-03365-9
     [Google Scholar]
  5. Kowal P, Dowd J. Definition of an older person. Proposed working definition of an older person in Africa for the MDS Project. 2001. https://doi.org/10.13140/2.1.5188.9286
     [Google Scholar]
  6. Dagar S, Emektar E, Uzunosmanoglu H, Corbacioglu SK, Oztekin O, Cevik Y. Risk of acute kidney injury after contrast-enhanced computed tomography in emergency department. Hong Kong J Emerg Med. 2022; 29:305–311.
    [Google Scholar]
  7. Özen Olcay H, Emektar E, Çorbacioğlu ŞK, Saral Öztürk Z, Akkan S, Çevik Y. A retrospective study of CT scan utilization in the emergency department for patients presenting with seizures. Am J Emerg Med. 2024; 80:132–137. https://doi.org/10.1016/j.ajem.2024.03.031
     [Google Scholar]
  8. Gilbert EH, Lowenstein SR, Koziol-McLain J, Barta DC, Steiner J. Chart reviews in emergency medicine research: where are the methods? Ann Emerg Med. 1996; 27:305–308. https://doi.org/10.1016/S0196-0644(96)70264-0
     [Google Scholar]
  9. Elm E von, Altman DG, Egger M, Pocock SJ, Gøtzsche PC, Vandenbroucke JP. The strengthening the reporting of observational studies in epidemiology (STROBE) statement: guidelines for reporting observational studies. J Clin Epidemiol. 2008; 61:344–349. https://doi.org/10.1016/j.jclinepi.2007.11.008
     [Google Scholar]
  10. Maeder M, Klein M, Fehr T, Rickli H. Contrast nephropathy: a review focusing on prevention. J Am Coll Cardiol. 2004; 44:1763–1771. https://doi.org/10.1016/j.jacc.2004.06.075
     [Google Scholar]
  11. Morcos SK, Thomsen HS, Webb JA. Contrast-media-induced nephrotoxicity: a consensus report. Contrast Media Safety Committee, European Society of Urogenital Radiology (ESUR). Eur Radiol. 1999; 9:1602–1613. https://doi.org/10.1007/s003300050894
     [Google Scholar]
  12. Kulkarni CS, Kothari JP, Sirsat RA, Almeida AF. A simplified risk score to estimate the risk of contrast-induced nephropathy after contrast exposure. Indian J Nephrol. 2023; 33:333–339. https://doi.org/10.4103/ijn.IJN_65_21
     [Google Scholar]
  13. Eitzman EA, Kroll RG, Yelavarthy P, Sutton NR. Predicting contrast-induced renal complications. Interv Cardiol Clin. 2023; 12:499–513. https://doi.org/10.1016/j.iccl.2023.06.001
     [Google Scholar]
  14. Ayar Y, Ersoy A, Soyak H. Cirrhosis and renal dysfunction. Turk Nephrol Dial Transpl. 2016;25. https://doi.org/10.5262/tndt.2016.07
     [Google Scholar]
  15. Nayak SL, Maiwall R, Nandwani A, et al. Management of acute kidney injury in cirrhosis. Hepatol Int. 2013; 7:813–819. https://doi.org/10.1007/s12072-013-9456-x
     [Google Scholar]
  16. Sezer S, Külah E, Özdemir FN. Hipertansiyonun renal komplikasyonlar ve böbrek hastaliginin progresyonundaki rolü Official Journal of the Turkish Society of Nephrology 2003; 12:(2):67–73.
    [Google Scholar]
  17. Parfrey PS, Griffiths SM, Barrett BJ, et al. Contrast material-induced renal failure in patients with diabetes mellitus, renal insufficiency, or both. A prospective controlled study. N Engl J Med. 1989; 320:143–149. https://doi.org/10.1056/NEJM198901193200303
     [Google Scholar]
  18. Shirakabe A, Matsushita M, Shibata Y, et al. Organ dysfunction, injury, and failure in cardiogenic shock. J Intensive Care. 2023; 11:26. doi: 10.1186/s40560-023-00676-1
     [Google Scholar]
  19. Morcos SK. Prevention of contrast media nephrotoxicity—the story so far. Clin Radiol. 2004; 59:381–389. https://doi.org/10.1016/j.crad.2003.11.005
     [Google Scholar]
  20. Briguori C, Airoldi F, D’Andrea D, et al. Renal insufficiency following contrast media administration trial (remedial). Circulation. 2007; 115:1211–1217. https://doi.org/10.1161/CIRCULATIONAHA.106.687152
     [Google Scholar]
/content/journals/10.5339/jemtac.2025.14
Loading
Evaluation of the development and frequency of acute kidney injury in geriatric patients after intravenous contrast media use in the emergency department
Journal of Emergency Medicine, Trauma and Acute Care 2025, 14 (2025); https://doi.org/10.5339/jemtac.2025.14
/content/journals/10.5339/jemtac.2025.14
/content/journals/10.5339/jemtac.2025.14
Loading

Data & Media loading...

  • Article Type: Research Article
Keyword(s): contrast media, CT scan, emergency department and geriatric

Most Cited Most Cited RSS feed

This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error