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Qatar Foundation Annual Research Conference Proceedings Volume 2014 Issue 1
- Conference date: 18-19 Nov 2014
- Location: Qatar National Convention Center (QNCC), Doha, Qatar
- Volume number: 2014
- Published: 18 November 2014
251 - 300 of 480 results
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Hdl Cholesterol Efflux Predicts Graft Failure But Not Cardiovascular And Overall Mortality In Renal Transplant Recipients
More LessAims. A key function of high-density lipoprotein (HDL) particles in cardiovascular protection is cholesterol efflux, the removal of cholesterol from macrophage foam cells and first step in reverse cholesterol transport. This study prospectively investigated whether HDL cholesterol efflux capacity is associated with cardiovascular mortality, all-cause mortality, and graft failure in renal transplant recipients, patients with accelerated Read More
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Evaluation Of Regenerative Potential Of Pulp -derived Stem Cells And Gingival-derived Stem Cells In The Regeneration Of Periodontal Defects (experimental Study)
More LessAbstract Gingival tissue-derived mesenchymal stem cells (GMSCs) were recently identified and characterized as having multipotential differentiation and immunomodulatory properties in vitro and in vivo, and they represent new postnatal stem cell types for cytotherapy and regenerative medicine. Dental pulp stem cells (DPSCs) have very low morbidity, high efficiency and extensive differentiation ability. This study aimed a Read More
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Building Pharmacy Practice Research Capacity In Hamad Medical Corporation, Qatar
More LessTaking forward the research agenda: assessing the needs of pharmacists employed by Hamad Medical Corporation in Qatar Background and Objective: Traditionally, pharmacists in Qatar have very limited formal training related to research. The aim was to determine the needs of Hamad Medical Corporation (the principal public healthcare provider) pharmacists in relation to research education, training and practice. Settin Read More
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Deciphering The Sources Of Population-wide Variation In The Date Fruit Metabolome
More LessAuthors: Ilhame Diboun, Sweety Mathew, Maria Torres, Joel Malek and Karsten SuhreDates are important dietary component in the Arab region. Dates production in Qatar is essential for the country's long term food security plan. In this project, we set to investigate the global sources of variation in the dates metabolome. To this end, fully ripened date samples from 138 different varieties were collected from 14 countries including Morocco, Algeria, Tunisia, Libya, Egypt, Sudan, Jordan, Saudi Arabia, UAE, Read More
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Survey Among Healthcare Professionals On The Implications Of Pharmacogenetics And Its Limitations
More LessAuthors: Dania Alkhiyami, Dima Alsahan, Ahmed Abdelbari and Hazem ElewaPharmacists are expected to play an important role in applying pharmacogenetic discoveries to patient care. Despite the increased attention to genetic research in Qatar, clinicians' attitude towards pharmacogenetics' applications are not yet explored. Purpose: To determine the level of awareness, and perceived clinical implications of pharmacogenetics among health care professionals (physicians and pharmacists) in Q Read More
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The Characteristic And Outcome Of Foreign Body (fb) In Children In The State Of Qatar
More LessBackground: There are many children who present with a problem of Foreign Body (FB) that can be inserted in different orifices of their body like nose, ears or that are ingested in to their gut or being aspirated to their trachea or bronchioles. FB can be even life threating especially in case of chocking and potential of obstructing child's airway, or ingestion of sharp objects, magnetics, or batteries that may contribute to a lot of Read More
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Linked Data Based Semantically Enabled Electronic Medical Record Systems
More LessElectronic Medical Record (EMR) systems are information systems keeping electronic versions of patients' medical records. The use of EMR systems has been steadily increasing in recent years, due to many potential benefits. A fully functional EMR system can record patient demographic and chart data, keep track of vital signs, current medications, drug allergies and many other important facets of the patie Read More
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Ultrasound Image Enhancement Using An Adaptive Anisotropic Diffusion Filter
More LessAuthors: Yassine Toufique and Othmane BouhaliUltrasound imaging system is an important imaging modality for the diagnosis of most pathology. However, in certain situations the accuracy of diagnosis can be altered due to the speckle noise that affects these images, which can lead to a misdiagnosis. Ultrasonic speckle is an interference effect caused by the scattering of the ultrasonic beam from microscopic tissues inhomogeneities. To curb this difficulty many despecklin Read More
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Safety And Efficacy Of Ara 290, A Non-erythropoietic Peptide Engineered From Erythropoietin, In Patients With Painful Diabetic Neuropathy
More LessHuman diabetic neuropathy is the commonest long-term complication of diabetes and leads to pain, impotence, foot ulceration and amputation. Currently there are no FDA approved therapies for human diabetic neuropathy. ARA 290 is a novel non-hematopoietic peptide designed from the structure of erythropoietin to preferentially interact with the innate repair receptor that mediates tissue protection and repair. It has sho Read More
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Vitamin D Deficiency Among The Elderly: Insights From Qatar
More LessBackground: Vitamin D(VitD) deficiency is associated with co-morbidities in the elderly. VitD deficiency remains an under recognized problem in the general population and is poorly defined in elderly patients. In a geriatric population, VitD deficiency has been associated with poor muscular, physical and cognitive physical performance as well as falls and fractures. VitD deficiency is significantly associated with older age and e Read More
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Community Oriented Program For The Control Of Rheumatic Diseases (copcord)in Qatar
More LessAuthors: Housam Aldeen Sarakbi, Mohammed Hammoudeh, Abdul Razzakh Poil, Abdo Lutf and Ayah ZiyadaObjective: Community Oriented Program for the Control of Rheumatic Disease (COPCORD) were done in many countries to estimate the prevalence of rheumatic disease, we conducted COPCORD in Qatar for ages 16 and above for Qatari National of both sexes Methods: this is a cross sectional study with target of 1000 subjects, 500 males and 500 females. We conducted door to door survey using COPCORD Questionn Read More
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Screening For Diabetes In Ramadan - A Pilot Study
More LessAuthors: Meis Alkasem, Manal Othman, Ragae Dughosh and Abdul-badi Abou-samraDiabetes is highly prevalent in Qatar and about 1/3 of patients are not aware of their diseases. Screening for undiagnosed diabetes is essential for effective management and prevention of diabetes and its complications. The effectiveness and cost analysis of several diabetes screening programs have been the subject of intensive investigation. Point of care (POC) measurement of capillary blood glucose (CBG) is very sim Read More
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Epidemiological Differences Of Blinding Corneal Ectasia In Qatari Vs. Levante Arab Populations In Qatar
More LessAuthors: Alexander A Bialasiewicz, Katharina Breidenbach, Hynd Mebarki and Rana Al-aryanObjectives: To report on the differences of blinding corneal ectasias in Qatari vs. Levante Arab patient populations with two diagnostic set-ups. Methods: Group 1: Over 6 months, 6432 consecutive patients were assessed by PENTACAM HR PREMIUM, 65 index persons (IP) (128 eyes) followed for 1 year. Group 2: Over 15 months 3232 patients were assessed by NIDEK OPD ARK 10000, 35 IP (67 eyes) followed. Demographic, fu Read More
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Regulation Of Erk Phosphorylation In Calreticulin Knockout Mouse Embryonic Fibroblast Cells
More LessAuthors: Ghada Mubarak, Nasrin Mesaeli and Hamid MassaeliExtracellular signal regulated kinase (ERK1/2) is a member of the mitogen-activated protein kinase pathway (MAPK). ERK1/2 has a wide variety of functions including cell proliferation, differentiation, and migration to name a few. Thus alteration in the ERK1/2 pathway can result in different pathologies such as cancer, cardiovascular diseases and diabetes. ERK MAP kinase is activated through binding of extracellular growth f Read More
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Evaluating Psychosocial Support Needs Of Female Cancer Patients In The State Of Qatar
More LessAuthors: Razzan Alagraa, Ahmad Abujaber, Joanne Doughty and Prem ChandraBackground & Objectives Patient perceived perceptions of psychosocial support are increasingly important to understanding appropriate holistic patient centred care. Psychological distress amongst female cancer patients has been discussed at length in the literature. Psychosocial distress has been noted to increase steadily even after treatment if left untreated and is found to hinder recovery and physical coping with the d Read More
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Group Gene/protein Function Prediction
More LessAuthors: Ishita Khan and Reda RawiFunctional annotation of genes and their protein products is an essential step in the course of genome analysis. Experimental functional analysis techniques such as microarray or yeast two-hybrid systems simply can not handle the quantity of sequences made available by next-generation sequence technologies, and thus annotation of gene products is primarily predicted applying computational tools. A variety of computati Read More
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Autophagy Retards Inflammatory Mrna Decay And Elicits A White Phenotype During Adipocyte Maturation
More LessAuthors: Jingxuan Shan, Andrea Guennoun, Remy Thomas and Lotfi ChouchaneBackground: Recently, the role of autophagy in glucose and lipid metabolism has been emerging. Mice experiments showed that autophagy deficiency could prevent diet-induced obesity, characterized by less fat and a browning phenotype of white adipocyte (WAT). However, the underlying molecular mechanism is not well explored and the data from human are limited. Method: The mRNA sequencing data of undi Read More
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Comprehensive Characterization Of The Differentiation Of Human Embryonic Stem Cells Into Mesenchymal Stem Cells
More LessMesenchymal stem cells (MSC) are self-renewing multipotent cells which hold great potential in reconstructive medicine and tissue engineering. They have the ability to differentiate into cells of the mesoderm lineage and have been shown to be beneficial for the treatment of a variety of diseases. MSC can be derived from multiple adult tissues but have only limited expansion capacity in cell culture. Highly proliferative ESC Read More
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Understanding Susceptibility Gene Loci Of Gestational Diabetes Mellitus
More LessBy Sadia MunirOne of the fundamental goals of genetic research is to understand the pattern of heritability associated with the manifestation of various complex diseases. Elucidation of underlying genetic variation associated with common traits is one of the major challenges faced by clinical researchers. Gestational diabetes Mellitus (GDM) is multifactorial disorder of pregnancy. GDM refers to abnormal glucose tolerance that is first identifi Read More
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Protective Effect Of Eurycoma Longifolia On Uterine Adhesion Induced By Coitus In Estradiol Valerate Treated Female Rats
More LessAuthors: Mahfoudh Abdulghani, Abas Hussin, Siti Amrah Sulaiman and Chan LamIntroduction and objective: Adhesion can be defined as fibrous bands of scar-like tissue that appear between two surfaces inside the body. Tissue adhesion formation is one of the common problems in postoperative lower abdomen or uterus in reproductive organs; it can lead to severe complications such as pain and infertility. The objective of this study was to evaluate the effect of standardised extract of Eurycoma long Read More
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Sick Building Syndrome And Detection Of Volatile Organic Compounds With An Electronic Nose
More LessAuthors: Muhammad Hassan, Amine Bermak, Amine Ait Si Ali and Abbes AmiraBackground: Sick building syndrome (SBS) describes a situation in which building occupants experience mild to severe health problems for no perceptible reason. Indoor volatile organic compounds (VOCs), namely benzene (C6H6) and formaldehyde (CH2O) are considered as potential contributors to the SBS condition. Based on sufficient evidence of carcinogenicity from studies of human cancer and their exposure to b Read More
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Protein Kinase D1 Regulates Erα-positive Breast Cancer Cell Growth Response To 17βestradiol And Contributes To Poor Prognosis In Patients
More LessAuthors: Manale Karam, Ivan Bièche, Christine Legay, Sophie Vacher, Christian Auclair and Jean-marc RicortAbout 70% of human breast cancers express and are dependent for growth on estrogen receptor α (ERα), and therefore are sensitive to antiestrogen therapies. However, progression to an advanced more aggressive phenotype is associated with acquisition of resistance to antiestrogens and/or invasive potential. In the present study, we highlight the role of the serine/threonine-protein kinase D1 (PKD1) in ER Read More
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Prevalence And Association Of Periodontal Disease Among Rheumatoid Arthritis Patients In Qatar: A Cross Sectional Study
More LessAuthors: Mohammed Hammoudeh, Ahmed Al-momani, Magdi Abdelrahman, Prem Chandra and Samer HammoudehBackground: Rheumatoid arthritis is an autoimmune disease, associated with a chronic inflammatory status, and an increased level of cytokines which are implicated in the destruction of joints. Periodontal disease is an infection of the tissue that surrounds and supports the tooth structure, resulting also in a chronic inflammatory status. An association between the two diseases has been reported in numerous studies. Objecti Read More
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A Fully Functional Secure Ubiquitous Healthcare Monitoring System
More LessI. BACKGROUND & O BJECTIVES Recent advances in sensing, communication and actuation are leading to the next generation of Telemedicine when integrated with Wireless Body Area Networks (WBANs). They have a great potential in fostering the provision of next-generation Ubiquitous Healthcare (U-Health). However, deploying new technologies in healthcare applications without considering security makes patient priva Read More
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Regulation Of Caveolin-dependent Endocytosis By Endoplasmic Reticulum Chaperones
More LessAuthors: Hamid Massaeli, Divya Viswanathan, Dhanya Pillai and Nasrin MesaeliCalreticulin (CRT) is an endoplasmic reticulum chaperone protein that is involved in quality control process during protein folding and maturation. It plays an important role as a regulator of intracellular calcium homeostasis. Previously it has been shown that loss of CRT protein results in endoplasmic reticulum stress, increase in ubiquitin-proteasome activity, and resistance to apoptosis. Our preliminary studies illustrated t Read More
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Genomics And Molecular Genetic Diagnostic Outcomes Of Wcmcq-neurogenetics Research Lab. A Contribution To Health Care In Qatar
More LessAuthors: Alice Abdel Aleem, Mahmoud F. Elsaid and Khalid IbrahimCombined clinical, neuroimaging, genomics, and molecular genetics research efforts between neuropediatrics clinic at HMC, international clinical collaborators, and neurogentics lab at WCMCQ has successfully enabled a prominent achievement in providing tools and defined strategy for diagnostics, and primary prevention, carrier detection and prenatal intervention, of a wide variety of neurogenetics diseases encountere Read More
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One-pot Semisynthesis Of Exon1 Of The Mutant Huntingtin Protein: An Important Advance Towards Elucidating The Molecular And Structural Determinants Of Huntingtin's Aggregation And Toxicity
More LessAuthors: Anass Chiki, Ritwik Burai, Sophie Vieweg, Sean Deguire and Hilal Ahmed LashuelHuntington's disease (HD) is a fatal genetic neurodegenerative disorder caused by a CAG expansion gene which is translated into a polyglutamine stretch within the first exon of the Huntingtin protein (Htt). HD patients suffer from motor impairments, cognitive decline and depression. A hallmark of HD pathogenesis is the loss of neurons in the striatum and cortex which is closely linked to the formation of large cytoplasmi Read More
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How Does Health Data Collected Electronically Compare To The Data From The Standard Paper System?
More LessAuthors: Suzana Brown and Patrick McsharryWe develop a mobile application for Community Health Workers (CHWs) to collect health data for monitoring children's growth and development with a custom mobile application. The application is designed to be delay tolerant and optimized for low-resource settings. The evaluation is carried out in an urban and a rural location in Rwanda. The preliminary results show that CHWs are very successful in electronic data collection Read More
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Metabolomics Of Type Ii Diabetes In The Qatari Population
More LessAuthors: Noha A. Yousri, Dennis Mook-kanamori, Gabi Kastenmüller and Karsten SuhreBackground: Diabetes is one of the world's most rapidly growing metabolic disorders. In Qatar, one in five people may develop Diabetes. Despite the existence of well known metabolic biomarkers of diabetes, there is still an urgent need to study whether such markers are different in the Qatari population and investigate the interactions between metabolites to understand the underlying metabolism of such disorder. Wher Read More
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C-Abl Phosphorylates Alpha-synuclein And Regulates Its Degradation, Implication For Alpha-synuclein Clearance And Contribution To The Pathogenesis Of Parkinson's Disease
More LessIncreasing evidence suggests that the c-Abl protein tyrosine kinase could play a role in the pathogenesis of Parkinson's disease (PD) and other neurodegenerative disorders. c-Abl has been shown to regulate the degradation of two proteins implicated in the pathogenesis of PD, parkin and alpha-synuclein (alpha-syn). The inhibition of parkin's neuroprotective functions is regulated by c-Abl-mediated phosphorylation of parkin Read More
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Inferring Copy Number Variation Networks From The Qatari Genome
More LessAuthors: Noha A. Yousri, Khalid A. Fakhro, Ronald G. Crystal and Karsten SuhreBackground: Thousands of Copy Number Variations (CNVs) obtained from Next Generation Sequencing (NGS) technologies present a rich information for biologists. Such huge information is tempting for discovering the inherent characteristics for a population's genome. Copy Number Variations (CNVs) are deletions and duplications in the genome, that may associate with certain phenotypic characteristics as diseases o Read More
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Srebp-2 Intronic Microrna 33a Post-translationally Controls Ldl Uptake
More LessAuthors: Vimal Ramachandran and S. Hani Najafi-shoushtariBackground and Objectives Impaired cholesterol and fat metabolism contributes to obesity, type 2 diabetes and atherogenic cardiovascular disease; major chronic conditions that are increasingly prevalent in Qatar. There is thus an urgent need for new treatment modalities to combat the rise in these diseases. Understanding how cholesterol/lipid homeostasis is achieved and maintained is among the very first critical steps Read More
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MicroRNA Regulation Of Annexin A2/p11 System Implicated In Diabetic Retinopathy
More LessBackground & Objectives Diabetic retinopathy is the most frequent cause of blindness among working-age adults in the industrialized world and, among Qataris over the age of 40 with diabetes, has a prevalence of 31.8%. Diabetic retinopathy begins when metabolic changes and alterations in vascular perfusion cause capillary leakage and closure, due to dropout of pericytes, cells that stabilizes microvessels. Annexin A2 (A2), a Read More
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Thymidylate Kinase - An NMR Based Approach For Drug Discovery
More LessBy Gordon RuleThymidylate kinases (TMKs) play a central role in the production of nucleotide precursors that are required for the replication of DNA. Consequently, this enzyme is a potential drug target for the discovery of anti-bacterial, anti-fungal, and anti-parasitic drugs. In addition, TMKs are also involved in the activation of prodrugs. In particular, the anti-HIV drug AZT is activated by human TMK (huTMK) and the low efficienc Read More
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Integrating Behavioral, Neural And (epi-)genetic Data Into A Model Of Psychobiological Development: The Example Of Stress
More LessBy Vanessa LuxIn a rapidly changing society, knowledge and education are key factors for indivdual well-being and social development. To create ideal learning environments and achieve both, it is important to know how our mind develops over the life span. This is also highly relevant for mental health and especially the prevention of psychological stress. On the other hand, the physiological stress reaction is considered to play a vital role in Read More
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Identification Of Post-translationally Modified Α-synuclein Protein In Biofluids Of Parkinson's Disease Patients Using A Targeted And Quantitative Mass Spectrometry Approach.
More LessAuthors: Céline Salomé Vocat, Bruno Fauvet, Michel Prudent, Adrien W. Schmid and Hilal A. LashuelIdentification of post-translationally modified α-Synuclein protein in biofluids of Parkinson's disease patients using a targeted and quantitative mass spectrometry approach. Céline Vocat1, Bruno Fauvet1, Michel Prudent4, Adrien W. Schmid3, Hilal A. Lashuel1&2. 1 Laboratory of Molecular and Chemical Biology of Neurodegeneration, Brain Mind Institute, Ecole Polytechnique Fédérale de Lausanne (EPFL), 1015 Lausanne, Switzerl Read More
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Evidence-based Stillbirth Prevention Strategies: Combining Empirical & Theoretical Paradigms To Inform Health Planning And Decision-making
More LessAuthors: Mary Lou King, Amna Aden, Stephany Tapa Daya, Reem Jumah and Salma KhanABSTRACT Introduction: A global health project undertaken in Qatar on the Arabian Peninsula immersed undergraduate nursing students in hands-on learning to address the question: what strategies are effective in preventing stillbirth? Worldwide stillbirth estimates of 2.6 million/year (Cousens et al., 2011) and the high rate in the Eastern Mediterranean Region (EMR) of 27/1000 total live births provided the stimulus for this inquir Read More
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Physiological Indices During Continuous And Sinusoidal Running Exercise In Football Players
More LessAuthors: Badrane Zinoubi, Sana Zbidi, Omar Hammouda, Henry Vandewalle and Tarak DrissIt is well established that intermittent exercises are very specific for performance in field and combat sports. However, few studies have examined the effect of sinusoidal oscillation in exercise intensity could maintain or ameliorates energetic coast. The aim of this work was to investigate if the variation of exercise allures (constant speed (CT-sp) vs. sinusoidal speed (SIN-sp) on physiological responses during submaximal exercis Read More
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Qatar Digital Healthcare: An Impact Assessment Of Health Information Technologies On National Capacity Development
More LessBy Rashid NiazBackground The health system in Qatar is going through a digital health technology transformation. Along with upgrading its facilities and medical equipment, Qatar has invested hundreds of millions of Riyals in health information systems specifically deployment of an integrated Electronic Medical Record (EMR) across its national hospitals and primary health care centers. This has introduced the age of health informatics for Read More
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Harmonic-field Based Artery Separation From Cerebral Aneurysm For Stent Deployment
More LessBackground & Objective: Cerebral aneurysms are one of the prevalent and devastating cerebrovascular diseases of adult population worldwide. The resulting effect is subarachnoid hemorrhage, intra- cerebral hematoma and other complications leading to a high mortality rate. When the aneurysm is fusiform, having wide neck or is large in shape, deploying stent in the parent artery to bypass aneurysm is considered as th Read More
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Preliminary Design Of An Actuated Probe For Enhance Visualization In Robotic Surgeries
More LessINTRODUCTION: Robotic surgery allows minimally invasive procedures to be performed with greater precision, higher dexterity, and ergonomic comfort. The widely used daVinci surgical robot (Intuitive Surgical, California, USA) consists of a central stereoscopic camera and three robotic surgical arms controlled by the surgeon using a console. Though the stereoscopic camera provides superior visualization of the surgical Read More
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Comparison Of In Vitro Models Of Diabetic Nephropathy Using Renal Tubular Cells
More LessAuthors: Heba El Gamal and Shankar MunusamyBackground: Diabetic nephropathy (DN) is a chronic and serious complication associated with diabetes. The standardization of an in vitro model to best represent DN is very challenging due to the chronic nature of the condition. Therefore, two different renal tubule cell lines - Madin-Darby canine kidney cells (MDCK) and Normal rat kidney cells (NRK-52E) - were used to investigate the effects of high glucose on kidney cells. Read More
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Three-dimensional Electrospun Biodegradable Nanofibers Scaffolds Loaded With Amoxicillin For Wound Healing Applications: Preparation & Characterization
More LessAuthors: Fatemeh Jalali, Oraib Abdallah, Somayeh Zamani and Husam YounesBackground: The use of electrospinning technology (ET) in fabrication of three-dimensional biodegradable electrospun nanofibers scaffolds (BENS) has recently gained considerable attention in tissue engineering. BENS are superior to other existing scaffolds in tissue regeneration as they provide high surface area-to-volume ratio, possess high porosity, and offer a biomimetic environment in a nanometer scale. Objectives: To fabri Read More
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Postprandial Hyperinsulinaemia And Hyperproinsulinaemia Are Early Predictors Of Cardiovascular Disease In Apparently Healthy Young Qatari Women
More LessBackground. Insulin resistance and the prevalence of diabetes are high in the Middle Eastern population and in people of South Asian origin. Because of epidemic proportions that diseases have reached in these populations. It is important to find early markers along with preventative interventions. Recent data indicates that the metabolic defect in the pre-diabetic condition relates more strongly to post-prandial deficie Read More
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Synthesis And Pharmacological Screening Of Novel Piperine Analogs For Potential In Vitro Protection From Endoplasmic Reticulum Stress
More LessAuthors: Ayat Samir Hammad, Shankar Munusamy and Ashraf KhalilAbstract: Background: The endoplasmic reticulum (ER) is the chief organelle involved in protein homeostasis. Perturbations to the ER protein folding machinery caused by hyperlipidemia, hyperglycemia or hypoglycemia has been shown to trigger ER stress and activate the unfolded protein response (UPR) as a defense mechanism. Accumulating evidences implicate the role of ER stress in the development of chronic kidney d Read More
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Body Size, Physical Activity And Risk Of Cancers Of The Breast, Prostate And Colorectum Among Diabetic Patients
More LessAuthors: Kawthar Al-dabhani, Marc Gunter and Neil MurphyABSTRACT Introduction Over the last 30 years the incidences of cancer and diabetes have been increasing progressively and there is both epidemiologic and experimental data linking diabetes and various cancer outcomes. Previous studies has shown that physical activity, height, and obesity; measured by weight, waist circumference, waist-to-hip ratio and body mass index were associated with the risk of diabetes and Read More
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The 16p11.2 Deletion In An Extremely Obese Patient From Qatar
More LessObesity is a highly heritable trait, with estimated heritability of about 40-70%. Genetic variations including single nucleotide polymorphisms (SNPs) and copy number variations (CNVs) have been associated with obesity. A large deletion (~600 kb) on chr16p11.2 has been found to cause a highly penetrant from of obesity often associated with hyperphagia and intellectual disabilities, in European populations. Here, we investigated Read More
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Detecting Cardiovascular Abnormalities Using A Telemetry System Based On Arduino Microcontroller & Smartphones
More LessAuthors: Faiyadh Shahid, Abdulla Baobeid and Reza TafreshiThis project focuses on developing a complete telemetry system in response to the growing demand for efficient, mobile and inexpensive system for detecting cardiovascular abnormalities. Our team has already developed two algorithms. The first algorithm detects various critical points on Electrocardiograph (ECG) waveforms such as: P-wave, QRS complex, T-wave and ST elevation. Based on these points, the second algorit Read More
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Transtubular Supraorbital Approach
More LessBackground: Brain retraction has been shown to cause brain trauma and consequent neurological deficits, as well as closure of blood vessels due to applied pressure from the retractor. Hence it becomes necessary to explore alternative means for intracranial procedures that minimize brain retraction, such as keyhole techniques. Such techniques offer minimally invasive means that reduce brain retraction, effectively reducin Read More
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Aqueous Extract Of Origanum Syriacum Inhibits Proliferation, Migration, Adhesion As Well As Erk1/2 Phosphorylation In Aggressive Breast Cancer
More LessAuthors: Amal Al Kahlout and Ali EidBackground: Breast Cancer is one of the leading causes of cancer related mortality in women, both in Qatar and the world. Despite the available treatments the incidence of breast cancer is increasing. This highlights the need for new approaches for cancer. One of the fields that is gaining attention nowadays is herbal medicine. Herbs are known to have bioactive compounds that affect many diseases one of which is cancer. Read More
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