Qatar Foundation Annual Research Conference Proceedings Volume 2016 Issue 1

Background & Objectives Epilepsy is a neurological disorder that is associated with repeated episodes of seizures. In epilepsy, the normal pattern of neural activity is disturbed, causing the patient to experience various symptoms ranging from staring blanking for a few seconds to long periods of vigorous convulsions and unconsciousness. In many patients, the injuries they endure are a direct result of the confusion, loss of muscle Read More

Background Maternal health refers to the health of women pre-pregnancy, during pregnancy, childbirth and postpartum. Pregnancy is a state of altered physiology and medication use during this period is remarkably challenging. For various reasons medication use during pregnancy cannot be completely avoided however, due to altered drug pharmacokinetics and crossing of placenta many of these drugs could significantly Read More

Calreticulin is a molecular chaperone responsible for proper protein folding in the endoplasmic reticulum (ER), and supports assembly of protein oligomers. Calreticulin also plays a role in quality control of protein expression in the ER. Calreticulin is a ubiquitous protein that shows high levels of expression in fetal cardiomyocytes. Both knockout and over-expression of Calreticulin in the mouse embryos is lethal arguing for an imp Read More

The study includes the isolation and extraction of some active molecules like (flavonoid and total poly phenolic) and plant insulin (Glucokinin) from leaves and flowers of B. variegate L. belonging to the family Leguminosae which cultivated in Iraq. Also the study employed an in vivo evaluation of Bauhinia leaves (petroleum ether and methanol extract) and methanol extract and flowers extraction in mice at concentrations (200 an Read More

Introduction Blood cultures are commonly performed in hospitals daily as it is employed to detect infections that are spreading through the bloodstream (eg; bacteremia, septicemia). This is possible because the bloodstream is usually a sterile environment. Positive blood cultures indicate either bacteremia, or false positive blood cultures from contamination with bacterial skin flora through improper technique. False positiv Read More

Background Chronic myeloid leukemia is characterized by the reciprocal chromosomal translocation t(9;22)(q34;q11), leading to the formation of the Philadelphia chromosome. This encodes the constitutively active Bcr-Abl tyrosine kinase, which profoundly affects proliferation, apoptosis, and cell adhesion signaling pathways. Despite remarkable success in controlling CML at chronic phase by Bcr-Abl tyrosine kinase inhibitors (T Read More

Introduction Accumulating evidence suggests that adipose tissue is a dynamic organ that undergoes expansion and contraction in response to energy demands and obesity-associated tissue injury. The dynamic nature of the adipose tissue is achieved via changes in both size and number of mature adipocytes through adipocyte hypertrophy and preadipocytes proliferation and differentiation respectively. These changes are Read More

Objective To evaluate the concordance of Pap smear, Colposcopy and histopathology in patients with cervical intraepithelial neoplasia (CIN) in a local tertiary care hospital. Design Retrospective descriptive study. Materials and methods All patient with CIN undergoing LLETZ during the period from January 2007 to July 2013 were included in the study. Case records were reviewed regarding demographics and clinical data, Pap s Read More