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Qatar Foundation Annual Research Conference Proceedings Volume 2016 Issue 1
- Conference date: 22-23 Mar 2016
- Location: Qatar National Convention Center (QNCC), Doha, Qatar
- Volume number: 2016
- Published: 21 March 2016
421 - 440 of 656 results
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oa Modified Silk with Cell-Adhesive and Non-Thrombogenic Properties as a Tissue Engineering Substrate
Authors: Matthias Gabriel, Marc Becker and Christian Friedrich VahlIntroduction Replacement of damaged tissue is nowadays an aim of tissue engineering. This technique involves the use of porous or fibrous structures – the so-called scaffolds – that support the colonization with the desired cell type and which are degraded after fulfilling their temporary supporting function. Basic requirements for the prevailing materials used in this field are nontoxicity, low immunogenicity and cell-adhes Read More
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oa An Organic Field Effect Transistor Based Nano Biosensor for the Early Detection of Cardio Vascular Disease – The Most Common Death Causing Disease in Qatar
More LessQatar has one of the world's fastest growing population. The lifestyle and socio-economic situation of the Qatar, like other Arab countries are also vastly changing according to the growing trends. These changes finally reflected in the life expectancy and led to a rise in the “Non-Communicable diseases” or otherwise known as the diseases of longevity like Cancer, Cardio Vascular Diseases (CVD), Diabetes Mellitus (DM), Asthma, Read More
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oa Improving Insulin Therapy Related Knowledge in Type 2 DM Among Physicians in West-Bay Health Center
Authors: Islam Ahmed Noureldin and Amal Al AliBackground Studies show that diabetics are in high risk for complications, hospitalization, and death from uncontrollability. Good Glycemic control is an important part of preventive services for diabetic complications. One of the most important treatment options for Diabetic patient is insulin therapy, however there is evidence of poor physician knowledge about types and modalities of insulin therapy. Lack of knowledge will in Read More
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oa Time Course of Platelet Activation Markers as a Potential Prognostic Indicator after Primary Percutaneous Coronary Angioplasty in Qatar
Rationale Myocardial infarction (MI) is one of the leading causes of death and disability worldwide. In Qatar specifically, cardiovascular diseases account for 20% of the main causes of death in the country, and the cases of MI is rising rapidly. Recent developments in the management of MI, particularly the emergent opening of the Culprit artery by primary percutaneous coronary intervention (PPCI), have resulted in significan Read More
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oa Synthesis, Characterization, Crystal Structures, and in vitro Antitumor Activity of Palladium and Platinum (Ii) Complexes with 2-Acetyl-4-Methylthiazole Thiosemicarbazone and 2-Acetylpyrazine Thiosemicarbazone
Authors: Hassan Nimir, Norah Al Mohaideb, Mariem Hamad, Awadelkareem Ali, Cenk Aktas, Volker Huch, Michael Veith and Uli RauchThe novel Schiff bases I HAMTTSC (2-Acetyl-4-methylthiazole thiosemicarbazone), II HAPTSC(2-Acetylpyrazine thiosemicarbazone) and their complexes with Pt(II) and Pd(II): 1 [Pt(AMTTSC)Cl], 2 [Pt(AMTTSC)2], 3 [Pd(AMTTSC)Cl], 4 [Pd(AMTTSC)2], 5 [Pt(APTSC)Cl], 6 [Pt(APTSC)2], 7 [Pd(APTSC)Cl], and 8 [Pd(APTSC)2] have been synthesized, and characterized by elemental analysis and spectroscopic studies. The cryst Read More
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oa 3D Alginate Scaffold for Anatomical Aortic Valve Tissue Engineering
Authors: Albert Ryszard Liberski and Magdi H YacoubBackground Within the field of biomedicine, alginate applications are numerous, from wound healing and cell transplantation to delivery of bioactive molecules. Recently, alginate based biomaterials are entering into clinical trials for the treatment of myocardial infarction (1). Due to its non-thrombogenic nature, this polymer is very promising for cardiac applications, including as scaffold for heart valve tissue engineering Read More
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oa Design an Expert System for the Diagnosis of Pulmonary Tuberculosis
By Rasha BadiPulmonary tuberculosis (PTB) is a common worldwide infection and a medical and social problem causing high mortality and morbidity, especially in developing countries. An expert system for diagnosis of this disease was designed based on expert's knowledge for providing decision support platform to assist fresh graduator (inexperienced) physicians, and other healthcare practitioners to arrive the final diagnosis of TB more Read More
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oa Comparative Expression Profile of Organic Cation Transporters in Diabetes and Cancer: Effects of Metformin
Authors: Rohit Upadhyay, Christopher R Triggle and Hong DingBackground and Aim Organic cation transporters have critical role for absorption, distribution, metabolism, and elimination of many endogenous small organic cations as well as a wide array of drugs. These transporters act as uptake transporters (OCT1, OCT2, OCT3 and PMAT) or efflux transporters (MATE1 and MATE2) for cationic drugs including Metformin. PMAT, OCT1 and OCT3 are expressed in Intestine and may be i Read More
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oa Anti-Neoplastic Effects of Annonacin against Renal Cell Carcinoma
Authors: Shankar Munusamy, Akila Gopalakrishnan, Sreenithya Ravindran, Feras Alali and Ali H. EidBackground and Objectives Renal cell carcinoma is the most common and lethal form of all renal cancers, and accounts for 4.1% of all cancer cases in Qatar. Mutations to Von-Hippel Lindeau (VHL) gene in renal cells activates hypoxia inducible factor-1 alpha (HIF-1α) response pathway, and contributes to increased proliferation and progression to renal cell carcinoma. Hence, chemotherapeutic modalities available to treat re Read More
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oa Design of a Time-Frequency Algorithm for Automatic Eeg Artifact Removal
Authors: Boualem Boashash, Samir Ouelha and Sadiq Ali Maqsood1) The method The injuries suffered by newborns during birth are a major health issue. To improve the health outcomes of sick newborns using EEG measurements, a number of recent studies focused on the use of high-resolution Time-Frequency Distributions to extract critical information from the collected signals [1]. Several algorithms have been proposed. A major problem in the implementation of such algorithms for fully au Read More
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oa Reversal of Right Ventricular Hypertrophy and Dysfunction by Treprostinil in a Rat Model of Severe Angioproliferative Pulmonary Arterial Hypertension
More LessPurpose Pulmonary arterial hypertension (PAH) is a devastating cardiovascular disease of the pulmonary vasculature that remains poorly understood. Despite a number of available FDA approved drugs, survival remains low, reaching an estimated 5-year survival as low as 27%. This severe disease is characterized by dysfunction and eventual failure of the right ventricle (RV) of the heart. The main focus of therapeuti Read More
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oa Body Mass Index and Pattern of Diabetes in Qatar – A Retrospective Study of 529 Patients with Obesity
Authors: Manik Sharma, Saad Al Kaabi and Rajvir SinghBackground Qatar ranks among the top countries with highest prevalence of diabetes and obesity. Obesity is generally measured by a Body mass index (BMI). BMI has been found to be independent risk factor for development of diabetes. Also, diabetes when associated with obesity leads not only to its poor control but also causes increased long-term complications from diabetes. Aim To delineate the pattern of obesity among Read More
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oa How MERS-CoV Helped Overcome Communication Barriers in Qatar
Background As a conventional type of communication, health education usually face several barriers that make its outcome fall short. Among many, lack of interest, distraction, and rejection are well documented barriers to engaging audience in a communication process leading to behavioral change. Despite the novel corona virus which was responsible for the Middle East Respiratory Syndrome (MERS-CoV) created Read More
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oa A Hexokinase II Derived-Cell Penetrating Peptide Targets the Mitochondria and Triggers Apoptosis in Cancer Cells
More LessMost cancers are characterized by a high rate of glycolysis and overexpression of mitochondrial-bound isoforms of hexokinase, an enzyme that phosphorylates glucose in an ATP-dependent manner and this commences the first committed step in glucose metabolism. Type II hexokinase (HK II) plays a paramount role in metabolic reprogramming in tumors and its association with the voltage dependent anion channel (VDAC), Read More
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oa How Common is Bacterial Meningitis in Patients with Urinary Tract Infection below the Age of 60 Days?
More LessIntroduction Urinary tract infection (UTI) is one of the most common pediatric infections. UTI may be associated with bacteremia and even meningitis in small babies, warranting full septic work up including a cerebrospinal fluid (CSF), especially in infants below the age of 60 days. Literature regarding the co-existence of meningitis in infants diagnosed with UTI is conflicting. It is critical to be able to correctly identify Read More
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oa Double Network Hybrid Hydrogels with Nanocomposite Structures for Cartilage Tissue Engineering Applications
Authors: Ali Mohammed, Julian R Jones and Theoni GeorgiouHydrogels have become a popular source of research for cartilage tissue engineering but have been limited by their brittle nature at high water contents. Double network hydrogels (DNHG) are innovative materials that possess the ability to hold high water content whilst maintaining high mechanical strength, but require more accurate control over these properties. This study aims to achieve this goal by introducing a new Read More
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oa Using the Transtheoretical Model to Enhance Self-management Activities in Type 2 Diabetic Patients: A Systematic Review
By Yara ArafatBackground: Many health organizations are always highlighting the importance of health promotion, and disease prevention, due to the high incidence of chronic diseases that are spread worldwide and increasing continuously. One of the most prevalent chronic diseases is diabetes mellitus (DM). Many studies conducted in developed countries proved that lifestyle changes in patients resulted in a reduction in the pre Read More
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oa Development and Validation of an Allelic Frequency Database for Qatari Population using 13 Rapidly Mutating Y-Str Multiplex Assay
More LessDifferentiating male lineages using non-recombining Y-chromosomal genetic markers is highly informative for tracing human migration and for forensic studies. Recently, it has been shown that the level of male lineage resolution can be enhanced by analysing Rapidly Mutating (RM) Y-STRs. The aim of this study was to develop an allelic frequency database for Qatari population to evaluate the resolution power of 13 RM Y-ST Read More
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oa Prevalence of Gastrointestinal Protozoa in Feral Cat Population in Qatar
Introduction: Doha city has a high feral cat population that is estimated to outnumber its human inhabitants by 2-3:1 with a total population of 2-3 million cats according to Qatar Cat Control Unit (QCCU). Doha had a significant rodent problem for decades as in many cities throughout the world. It was difficult to control this huge rodent number. Therefore, cats were introduced in the 1960s, but without any consideration of the po Read More
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oa Enteric Protozoa Associated with Acute Diarrhea in Hospitalized Children in Qatar
Authors: Amal Ibrahim, Shaikha Al-Abduljabbar and Marawan Abou MadiIntroduction: Diarrhea is the passage of three or more watery stool in a period of 24 hours (WHO, 2013). Types of diarrhea include acute watery diarrhea, acute bloody diarrhea known as dysentery and persistent diarrhea (WHO, 2013). It is caused by an infection of different pathogens including bacteria, viruses and parasites through fecal–oral transmission (WHO, 2013). Moreover, it can also be caused by food intoleran Read More
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