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Volume 2013, Issue 1
  • ISSN: 0253-8253
  • EISSN: 2227-0426

Abstract

Blood samples were collected from 30 women with age ranged from 27–70 years after 3 cycles of chemotherapy. Sera were used for IgA, IgG, IgM, C3, C4, IL-6 and TNF-α estimation. After 3 cycles of chemotherapy, all the immunological parameters reduced except TNF-α. Patients who developed disease reoccurrence after chemotherapy exhibit a significantly higher IgA, C3, IL-6 and TNF-α levels after 3 cycles of chemotherapy than patients who did not (p < 0.05). Therefore, serum IgA, C3, IL-6 and TNF-α can be used as predictors for breast cancer reoccurrence.

© 2013 Mahdi, Al-Jowher, Ali, licensee Bloomsbury Qatar Foundation Journals.
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/content/journals/10.5339/qmj.2013.6
2013-11-01
2024-11-14
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References

  1. Munk ME, Emoto M. Functions of T-cell subsets and cytokines in mycobacterial infections. Eur Respir J Suppl. 1995; 20::668–675.
     [Google Scholar]
  2. Stout RD, Bottomly K. Antigen-specific activation of effector macrophages by IFN-gamma producing (Th1) T cell clones. Failure of IL-4-producing (Th2) T cell clones to activate effector function in macrophages. J Immunol. 1989; 142:3:760–765.
     [Google Scholar]
  3. Berberoglu U, Ceyhan B, Erçakmak N, Sezerdogdu V. The value of new tumor marker CA 15-3 in diagnosis and monitoring of patients with breast cancer. J Islamic Acad Sci. 1989; 2:2:113–117.
     [Google Scholar]
  4. Park BW, Oh JW, Kim JH, Park SH, Kim KS, Kim JH, Lee KS. Preoperative CA 15-3 and CEA serum levels as predictor for breast cancer outcomes. Ann Oncol. 2008; 19:4:675–681.
     [Google Scholar]
  5. Niculescu F, Rus HG, Retegan M. Persistent complement activation on tumor cells in breast cancer. Am J Pathol. 1992; 140:5:1039–1043.
     [Google Scholar]
  6. Nenova KE, Kovatchev DE. TNF-A levels in cachectic cancer patients. Arch Hellen Med. 2000; 17:6:619–622.
     [Google Scholar]
/content/journals/10.5339/qmj.2013.6
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Can IgA, C3, IL-6 and TNF-α act as predictors for reoccurrence of breast cancer among Iraqi women?
Qatar Medical Journal 2013, 6 (2013); https://doi.org/10.5339/qmj.2013.6
/content/journals/10.5339/qmj.2013.6
/content/journals/10.5339/qmj.2013.6
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Supplements

Supplementary File 1

  • Article Type: Short Communication
Keyword(s): Breast cancer, Complements, Immunoglobulines, Interleukines and Women

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