Journal of Local and Global Health Science - Volume 2013, Issue 1

Arsenic compounds have been known and used for centuries but their effects in living organisms still represent a large unknown. Arsenic compounds have paradoxical effects: they are threatening to human health, especially upon long-term exposure that can induce the development of cancer; however, they are used as drugs against cancer. This review focuses on the effects shown by clinically and environmentally relevant arsenic Read More

Breast cancer represents one of the most common cancers in women and is a major life threatening illness found all over the world. Therapy approaches include irradiation and surgery, with chemotherapy considered an important strategy to treat breast cancer. Platinum based anticancer drugs, such as cisplatin (cis-di-amino-dichloride-platin, CDDP), carboplatin, orthoplatin, etc., have been successfully used in breast cancer the Read More

Abstract Incidents of non-communicable diseases (NCD) like cardiovascular diseases, cancer, diabetes, and chronic respiratory disease have increased dramatically and are currently the leading causes of death worldwide. Their rising incidents coincide with the dramatic changes in industrialization and development of societies over the past few hundred years. Therefore, current lifestyle practices should be further explored to uncover novel Read More

Abstract Lead (Pb2+) is ubiquitously distributed in the environment and shows significant health effects in humans, especially in the nervous system. In this review we illustrate how (Pb2+) neurotoxicity is associated with its ability to partially mimic the function of Ca2+ and modifies synaptic transmission pre- and post-synaptically. As Pb2+ binds to calcium-binding sites it alters their functionality, ranging from reduced currents through voltage Read More

Context: Since menopause age is constant, an increase in life expectancy has resulted in an increase of the menopause period in women. Aims: This study was done to assess women's awareness level about symptoms and complications of menopause and methods of their prevention. Settings and design: This cross-sectional research was conducted on 220 women, 40 years of age or older referrals in selected health care centers. Metho Read More