Qatar Foundation Annual Research Forum Volume 2012 Issue 1

Background and Objectives: Both diabetes and cancer are prevalent diseases with increasing incidence worldwide and especially in countries that are undergoing rapid industrialization (i.e. Gulf countries). Epidemiological studies provide strong evidence that subjects with diabetes are at a significantly higher risk of developing many forms of cancer and in particular solid tumors including colorectal cancer. While diabetes an Read More

Background: People with diabetes-related peripheral neuropathy (DPN) frequently suffer from concomitant postural instability that can lead to falls, fractures, depression, anxiety, and decreased quality of life. Exercise has been demonstrated to be effective in improving balance. However, high demands of conventional balance programs might overtax DPN patients' ability to perform exercises correctly. This might in turn reduce Read More

Background and Objectives: The incidence of type 2 diabetes mellitus (T2DM) is increasing worldwide, and certain sub-populations appear especially vulnerable to developing the disease. In Qatar, the prevalence of T2DM in the adult population is approximately twice that in the USA. Qatar is ranked sixth in the world for diabetes prevalence. Risk of disease in the country is increasing with an apparent doubling of incid Read More

Consanguinity and endogamy is common in the Middle East resulting in higher frequency of autosomal recessive genetic disorders, in particular private or rare genetic conditions. Most of these diseases are due to homoallelic state of pathogenic variants, a direct consequence of founder effect and increased co-efficient of inbreeding. Advanced molecular genetic technologies such as next-generation sequencing (NGS) are Read More

Success in life can be directly related to the ability to communicate. Full interpersonal communication substantially enhances an individual's potential for education, employment, and independence. Therefore, it is imperative that the goal of augmentative and alternative communication (ACC) use be the most effective interactive communication possible. For more than three decades now, the field known as augmentativ Read More

Background and Objectives: The epidemiology of child injuries among infants and toddlers (IAT) in Qatar has not been fully described. This study will analyze the injury epidemiology of fatal and non-fatal injuries in IAT and provide recommendations for targeted injury prevention programs for IAT in Qatar. Method: Data from the Qatar statistics authority (QSA), Hamad Medical Corporation (HMC) Trauma Registry and the mortuary f Read More

Background and Objectives: Metabolic labeling with stable isotopes remains a prominent technique for comparative quantitative proteomics and stable isotope labeling with amino acids in cell culture (SILAC) is the most prominent approach used. However, despite its power the approach traditionally is limited if applied to complex tissue culture regiments as those required for human embryonic stem cells (hESC). Classic h Read More

Background and Objectives: Foodborne illness is a major hindrance to health advancement around the world and has been identified as a high priority in the Qatar National Food Security Program (QNFSP) master plan. Increased risk of illnesses is worsened by the ease of travel around the world, by an increase in global food and animal commodities trade, and by continued movement of large populations across vast areas. Read More

Background: Management of physical activity in patients with diabetic foot disease is poorly understood. There is paucity of data, more specifically evidence from a randomized study investigating the levels and profiles of physical activity in this population. This study explores the quantification of physical activity as a function of offloading modality in patients with diabetic foot ulcers. Method: Thirty eligible subjects with non-infec Read More