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Qatar Foundation Annual Research Forum Volume 2013 Issue 1
- Conference date: 24-25 Nov 2013
- Location: Qatar National Convention Center (QNCC), Doha, Qatar
- Volume number: 2013
- Published: 20 November 2013
201 - 250 of 541 results
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Protective role of 4-phenylbutyrate against palmitate-induced endoplasmic reticulum stress and renal cell injury
More LessBackground and Objectives: Obesity is recognized as a significant risk factor for the development of chronic kidney disease (CKD). Emerging studies indicate that endoplasmic reticulum (ER) stress play a major role in obesity-induced renal damage and the development of CKD in obese patients. Therapeutic interventions to ameliorate ER stress using 4-phenylbutyrate (4-PBA), a chemical chaperone, have been shown to prevent o Read More
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The Impact Of Viral Evolution And Frequency Of Variant Epitopes On Primary And Memory Hiv-1-Specific Cd8+ T Cell Responses
By Nada MelhemIt is not clear if HIV-1 variants lose the ability to prime naïve CD8+ cytotoxic T lymphocytes (CTL) during progressive, untreated infection. Answering this question is important for developing immunotherapeutic approaches for enhanced control of residual HIV-1 infection in persons on combination antiretroviral therapy (cART). We therefore conducted a comprehensive longitudinal analysis of viral evolution and its impact on primary Read More
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Coronary artery bypass graft patients in Qatar: Possibly the youngest with the highest incidence of diabetes in the world
More LessCoronary Artery Disease in Qatar: Coronary artery bypass graft (CABG) - population possibly the youngest with the highest incidence of diabetes in the world. CS Carr, M Abdulsamad, AM Alkhulaifi Objective: Coronary artery disease is a potentially life-threatening condition. At the Heart Hospital we have an internationally established surgical database to collect data on our cardiac surgical patients. We studied our isolated CABG p Read More
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Vitamin D Suppresses Hepcidin Expression In Macrophages
More LessBackground: Anemia of chronic disease (ACD) is highly prevalent among subjects with chronic kidney disease (CKD), rheumatoid arthritis, diabetes mellitus, and cancer as well as in elderly subjects. ACD is also highly associated with infections, severe trauma and critical illness. Anemia of chronic disease is immune driven and is associated with decreased quality of life, and increased mortality. Iron is an essential nutrient for erythr Read More
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Metformin Protects Against Glucose-Induced Mouse Microvascular Endothelial Cell (Mmec) Death
By Hong DingBackground and Objectives: Type 1 and type 2 diabetes are associated with an elevated incidence of cardiovascular disease. An early indicator of cardiovascular disease is endothelial dysfunction wherein there is a blunted blood flow response following activation of the endothelium. The elevated blood glucose associated with diabetes is thought to be a key factor associated with endothelial dysfunction and, in particular, t Read More
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Beliefs and values influencing breast cancer screening practices of Arabic-speaking women in Qatar
More LessIntroduction: Similar to many countries in the world, breast cancer is the most common cancer among women in the State of Qatar and the incidence rate is rising. Previous findings indicate women in Qatar are often diagnosed with breast cancer at advanced stages and their awareness of breast cancer screening (BCS) services and participation rates in screening activities are low. Previous studies indicate the need to un Read More
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HIV sero-discordancy can be predictive of HIV infectiousness in sub-Saharan Africa
More LessIntroduction: The majority of the population in reproductive age across sub-Saharan Africa is engaged in stable couples. At least half of the couples affected by HIV are sero-discordant (SDCs), that is couples where one of the partners is HIV infected while the other is not, with potential for HIV within-couple transmission. Countries of sub-Saharan Africa are characterized by varying levels of HIV sero-discordancy. HIV infectiousn Read More
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Auto-Regulation And Cerebral Blood Flow In Tia Patients Attending A Stroke/Tia Clinic: Implications For Stroke Prevention In Qatar
More LessBackground and objectives: Cerebral auto-regulation is an intrinsic protective mechanism guaranteeing hemodynamic integrity of cerebral circulation. It modulates cerebral blood flow (CBF) in order to meet regional perfusion demands despite variations in arterial blood pressure. Impaired cerebral auto-regulation is associated with poor functional and prognostic outcomes in patients with ischemic stroke. The aims Read More
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HIV Nef expression in an AIDS mouse model favors the accumulation of CD4+ Treg cells which retain important suppressive functions
By Zaher HannaHIV-1 infection causes depletion and/or dysfunction of distinct CD4+ T cell subsets and may affect these differently. Regulatory CD4+ CD25Hi Foxp3+ T cells (Treg) represent a distinct CD4+ T cell subset with suppressor activity. These cells play an important role in the regulation of self-tolerance and autoimmunity, and in the regulation of immune responses against cancerous tumors and pathogens. During HIV infection, Read More
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Epidemiology of candidemia in Qatar: Performance of MALDI-TOF MS for identification of candida species, species distribution, outcome and susceptibility pattern
More LessBlood stream infections due to Candida species cause significant morbidity and mortality in health care settings. This surveillance analysis describes the epidemiology, trend in species distribution and outcomes of candidemia in patients at Hamad hospital, Doha, Qatar. From January 2004 to December 2010, a total of 187 patients with 201 episodes of candidemia were identified. C. albicans was the most common species isol Read More
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QBB: The first Qatar public biobank: Participant feedback and observations
By Nahla AfifiQatar Biobank (QBB), the first very large scale, long-term public biorepository in Qatar, is designed to build a powerful research infrastructure for future investigations of the lifestyle, metabolic and genetic risk factors for the most frequent medical conditions in Qatar, namely diabetes, cardiovascular and respiratory diseases, obesity and cancer. Qatar Biobank's recruitment approach provides a model for public involve Read More
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Estrogen Receptor Α Gene And Vitamin K Epoxide Reductase (Vkorc1) Gene Haplotypes And Low Bmd In Palestinian Postmenopausal Women
More LessBackground Osteoporosis is a common skeletal disorder characterized by low bone mass and microarchetectual deterioration of bone tissue with increased susceptibility to fractures. Osteoporosis is considered a multifactorial polygenic disease. The prevalence of postmenopausal osteoporosis in Palestine, based on of BMD at femoral neck, total hip and spine was 24%, 14% and 29.7% respectively. Previous studies on the effect Read More
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Mimicking A Postprandial Increase In Glucose Has A Biphasic Action On Microvascular Function
More LessBackground and Objectives: The high morbidity and mortality associated with both type 1 and type 2 diabetes are closely associated with an elevated incidence of cardiovascular disease. The importance of good glycaemic control for the reduction of risk, notably of microvascular disease, has been emphasised by the results from clinical trials such as the DCCT for type 1 diabetes and UKPDS for type 2 diabetes. Data from c Read More
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The Application of Experimental Microdosimetry to Mixed-Field Neutron-Gamma Dosimetry
More LessAbsorbed Dose Distributions In Lineal Energy For Neutrons And Gamma Rays Were Measured Using Both A Tissue-Equivalent Walled Counter (Tepc) And A Graphite-Walled Low Pressure Proportional Counter (Gpc) In The Am-Be Neutron Source Facility At Uoit. A Series Of Measurements Were Performed With The Counters Filled With Propane-Based Te Gas (55.1% C3H8, 39.5% Co2 And 5.4% N2) At Operating Gas Pressures Corr Read More
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Do Qatar Community Pharmacists Prescribe And Dispense Acute Community-Acquired Gastroenteritis Medications Rationally To Patrons? A Mystery Patient Study
More LessDo Qatar Community Pharmacists Prescribe and Dispense Acute Community-Acquired Gastroenteritis Medications Rationally to Patrons? A Mystery Patient Study
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Low-Complexity Wireless Monitoring Of Respiratory Movements Using Ultra-Wideband Impulse Response Estimation
By Furrukh SanaMonitoring of respiratory rate and amplitudes of a human being has important medical applications such as in health monitoring as well as in diagnosis of respiratory illnesses and disorders such as the sleep apnea disorder. Currently used techniques for respiratory monitoring require patients to wear sensors and electrodes across the chest to measure the respiratory effort. Such techniques not only cause discomfort t Read More
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Continuous And Noninvasive Hemoglobin Monitoring Reduces Red Blood Cell Transfusion During Neurosurgery: A Prospective Cohort Study
By Wael AwadaContext: Continuous, noninvasive hemoglobin (SpHb) monitoring provides clinicians with real-time trending of changes or lack of changes in hemoglobin, which has the potential to alter red blood cell transfusion decision making. Objective: The objective was to evaluate the impact of SpHb monitoring on blood transfusions in high blood loss surgery. Design: Prospective cohort study. Setting: Tertiary academic hospital in Read More
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Monotherapy Versus Combination Gram Negative Empiric Antibiotic Therapy For Febrile Neutropenia In Children With Cancer
By Shane PawlukBackground: Children with cancer who are treated with intensive myelosuppressive chemotherapy or radiation therapy and develop neutropenia are at risk of developing life-threatening infections. In adult cancer patients with febrile neutropenia, some evidence suggests that there is no difference in efficacy between monotherapy and combination gram negative empiric antibiotic regimens. Outcomes of these different a Read More
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Analyzing Electrocardiograms Via Smartphone To Detect Cardiovascular Abnormalities
More LessCardiovascular diseases (CVD) are the leading cause of death globally. According to the World Health Organization, around 17.3 million people died from CVD in 2008, which is estimated to increase to 23 million annually by 2030. This calls for the exploitation of the latest technology to analyze and detect heart diseases in a timely fashion. Electrocardiogram (ECG) records the electrical activity of heart, and any irregularities in th Read More
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How Do Pharmacists Advise Diabetes Patient Self-Management During The Holy Month Of Ramadan?
More LessBackground Many diabetes patients choose to participate in the Ramadan fast despite medical and religious advice to the contrary. Pharmacists, especially in ambulatory care, are considered the most easily and readily accessible health care providers whose guidance can help ensure safe fasting for these patients. Objective The aim of this novel study is to describe Qatar pharmacists' current practice, knowledge, and attitu Read More
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Uncovering The Mechanisms Of Soft Tissue Injuries Associated With Acl Tear
More LessUncovering the Mechanisms of Soft Tissue Injuries Associated with ACL Tear
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Comparison Of Different Assays To Measure Antioxidant Capacity In Qatari Grown Food
More LessComparison of different assays to measure antioxidant capacity in Qatari grown food
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Synthesis And Pharmacological Screening Of Novel Piperine Derivatives As Potential Therapeutic Agents To Treat Chronic Kidney Disease
By Ayat HammadSynthesis and pharmacological screening of novel piperine derivatives as potential therapeutic agents to treat chronic kidney disease
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Bioinformatics applications for Bacteriophages and their pathogenic bacteria proteins Analysis
More LessIntroduction: E. coli is usually harmless to the host, sometimes causes diarrhoeal and other diseases in humans. In the meantime, S. aureus is the cause of a wide range of different kinds of major and minor pyogenic infections. Rational : The mechanical action of the bacteriophage on the selected bacteria species depend on their receptors that adsorb them to their hosts, some proteins of the bacterial outer membrane act Read More
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Epidemiological Study Of Patients Presenting With The First Seizure In Qatar.
More LessEpidemiological study of patients presenting with the first seizure in Qatar.
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Real-Time Gpu Implementation Of Correlation-Based Dense Matching Of Stereo Endoscopic Images For Surface Reconstruction
More LessReal-Time GPU Implementation of Correlation-Based Dense Matching of Stereo Endoscopic Images for Surface Reconstruction
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Patient-Specific Anatomy And Tissue Texture Models For Surgical Simulations
More LessPatient-Specific Anatomy and Tissue Texture Models for Surgical Simulations
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The Polyamine Binding Protein, Potd, Is Needed For Intracellular Establishment Of The Waterborne Pathogen Legionella Pneumophila
More LessThe Polyamine Binding Protein, PotD, Is Needed for Intracellular Establishment of the Waterborne Pathogen Legionella pneumophila
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Non-Motor Manifestations In Parkinson'S Disease: The Link Between Sense Of Smell, Subjective Visual Vertical (Svv) Perception And Micrographia
By Ali KhattabNon-motor manifestations in Parkinson's disease: The link between Sense of smell, subjective visual vertical (SVV) perception and micrographia
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Notch-Mediated Crosstalk Between Breast Cancer Cells And Endothelial Cells Induces A Transitional Endmt Phenotype Participating To An Endothelial Pro-Tumoral Niche
By Pegah GhiabiNotch-Mediated Crosstalk between Breast Cancer Cells and Endothelial Cells Induces a Transitional EndMT Phenotype Participating to an Endothelial Pro-tumoral Niche
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Sanad: Cognitive Behavioral Therapy For Smart Mobile Diabetes Management System Embedding Social Networking Platform
By Turki AlanziSANAD: Cognitive Behavioral Therapy for Smart Mobile Diabetes Management System Embedding Social Networking Platform
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Cross-Sectional Study Of Total And Central Body Fatness And C-Reactive Protein Among Qatari Men And Women: The Qatar Biobank Project
More LessCross-sectional study of total and central body fatness and c-reactive protein among Qatari men and women: The Qatar Biobank Project
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A Novel Bace-1 Inhibitor, F70Hab16 Reduces Oxidative Stress In Brain Tissues Of Scopolamine-Induced Amnesia In Mice
More LessA Novel Bace-1 Inhibitor, F70Hab16 Reduces Oxidative Stress In Brain Tissues Of Scopolamine-Induced Amnesia In Mice
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Running Mechanics And Spring-Mass Behaviour During Treadmill Repeated Sprints Are Different In Hypoxia And In Normoxia
More LessRunning mechanics and spring-mass behaviour during treadmill repeated sprints are different in hypoxia and in normoxia
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The comparison of Muscle strength and short-term endurance in the different periods of type 2 diabetes
By Boshra HatefBackground: patients with type 2 diabetes (T2DM) are subjected to reduction in the quality and oxidative capacity of muscles. The effect of duration of diabetes on the muscle endurance response is not clear and strength as well .The aim of this study was the assessment of strength and endurance of knee extensor and flexor in the patients with T2DM<10 and T2DM>10 years in comparison with age, sex, BMI, ABI and PAI Read More
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Characterization Of Growth Factor Receptor Signaling Upon Loss Of Endoplasmic Reticulum Chaperones
More LessCharacterization of growth factor receptor signaling upon loss of endoplasmic reticulum chaperones
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Development And Characterization Of Poly (Diol-Co-Tricarballylate) Biodegradable Matrices For Implantable Controlled Drug Delivery, Tissue Engineering And Other Biomedical Applications
More LessDevelopment and characterization of poly (diol-co-tricarballylate) biodegradable matrices for implantable controlled drug delivery, tissue engineering and other biomedical applications
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Standardization Of An In Vitro Model Of Diabetic Nephropathy Using Madin-Darby Canine Kidney Cells
More LessStandardization of an in vitro model of diabetic nephropathy using Madin-Darby Canine Kidney cells
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Development, Implementation, And Evaluation Of A Novel Medication Safety Health Promotion Program For Schoolchildren In Qatar
By Kyle WilbyDevelopment, Implementation, and Evaluation of a Novel Medication Safety Health Promotion Program for Schoolchildren in Qatar
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Etiologic Studies On Equine Motor Neuron Disease: A Natural Model For Als
More LessEtiologic Studies on Equine Motor Neuron Disease: A natural model for ALS
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Associations Of Single Nucleotide Polymorphisms(Rs2383207) On Chromosome 9P21 With Coronary Artery Diseases In Qatar
More LessAssociations of single nucleotide polymorphisms(rs2383207) on chromosome 9p21 with coronary artery diseases in Qatar
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Mechanism Of Regulation Of Extracellular Matrix Upon Endoplasmic Reticulum Stress
More LessMechanism of regulation of extracellular matrix upon endoplasmic reticulum stress
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Assessment Of Parylene C Thin Films For Heart Valve Tissue Engineering
By Isra MareiAssessment of Parylene C Thin Films for Heart Valve Tissue Engineering
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Nanotechnology Approaches To The Treatment Of Pulmonary Hypertension: Gold Nanoparticles And No-Release
By Nura MohamedNanotechnology approaches to the treatment of pulmonary hypertension: Gold nanoparticles and NO-release
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Ultra-Wideband Mimo Channel Characterization For Healthcare Applications
By Marwa QaraqeThe idea of deploying multiple wireless sensors around the human body to enable ubiquitous healthcare by measuring continuously all the physiological data of interest has received considerable attention. Ultra-wideband (UWB) is a promising communication technology for short-range communication scenarios like body-centric wireless network (BCWN) (i.e, in the area of medical healthcare). UWB is characterized by lo Read More
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Knowledge of Risk Factors for Spontaneous Abortion among Qatari Arab Women
By Nish PatelSpontaneous abortion affects one in four of all pregnancies (Crenin, 2001). The rate of spontaneous abortion among Qatari Arab women presenting to Women's Hospital, Doha, Qatar is 34% (Women's Hospital, 2012) compared to the next highest ethnic minority (Egyptian Arab women) at 18%. Understanding and modifying risk factors for spontaneous abortion may prevent future miscarriages. Purpose: To assess the level of kno Read More
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Analysis Of Whole Genome Sequencing Data Of The Arabian, Percheron And Miniature Horse
More LessWhole genome sequencing provides a rich and unprecedented collection of the existing genetic variation in a genome. The development of next generation sequencing (NGS) technologies has enabled a rapid and relatively inexpensive method for whole genome sequencing. The current archive of genetic variations in the horse is mostly based on the Thoroughbred mare used to generate the reference sequence (EquCab Read More
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Design And Synthesis Of New Monoamine Oxidase Inhibitors As Potential Neuroprotective Agents
More LessBackground and Objectives: Monoamine oxidase (MAO) catalyzes the biodegradation of biogenic amine neurotransmitters and a variety of xenobiotic amines. Selective MAO B inhibitors are used in the treatment of Parkinson's disease and other neurodegenerative diseases while selective MAO A inhibitors are known antidepressants. Piperazine and pyrazole rings are common moieties in several MAO inhibitors. Th Read More
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Investigating The Function And Substrate Specificity Of Histone Deacetylase Enzymes:New Synthetic Tools To Investigate The Role Of Hdacs In Cancer
More LessInvestigating the Function and Substrate Specificity of Histone Deacetylase Enzymes:New Synthetic Tools to Investigate the Role of HDACs in Cancer
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