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Volume 1 (2020) Number 2
  • EISSN: 2708-0463

Abstract

تهدف هذه الدارسة إلى تشخيص خميرة وتحديد بعض عوامل الضراوة، وقد أظهر توزيع المرضى المصابين بداء مبيضات الدم أن الفئة العمرية 50-65 سنة سجلت أعلى حالات الإصابة بداء المبيضات عند النساء والرجال المصابين بمرض سرطان الدم بنسبة 50% و37.9% على التوالي مقارنةً بحالات إصابة أقل بداء مبيضات الدم عند الفئة العمرية دون 17 سنة عند النساء والرجال بنسبة8.8% و13.5% على التوالي، في حين كانت حالات الإصابة عند الفئة العمرية 5-8 سنوات مرتفعة، وصلت إلى 18 إصابة بداء مبيضات الفم بنسبة 42% للأطفال المصابين بسرطان الدم مقارنة بالفئة العمرية 8-10 سنوات التي سجّلت حالات إصابة أقل بلغت 9 حالات بنسبة 21%. وقد سُجلت أعلى الإصابات بخميرة ()، إذ بلغت 59 عزلة بين النساء والرجال المصابين بسرطان الدم، في حين كانت الإصابة بخميرة () أقل بلغت عزلة واحدة فقط، بينما بلغت العزلات الفموية من الأطفال المصابين بسرطان الدم لخميرة ()13) عزلة، في حين سُجّل لخميرة () عزلتان فقط. وأظهرت خميرة أعلى تكوين للغشاء الحيوي (Biofilm) فكانت 48 عزلة توزعت بين 21 إنتاجًا قويًا و27 إنتاجًا ضعيفًا للغشاء، أما أقل الخمائر إنتاجًا للغشاء فكانت خميرة () في 6 عزلات توزعت بين 4 ذات إنتاج قوي واثنتين ضعيفتَي الإنتاج للغشاء الحيوي.

This study aimed for isolation and identification of Candida glabrata and identifying some virulence factors. The distribution of patients with candidemia thrush showed that the age group 50-65 years old recorded the highest incidence of candidiasis in female and male with leukemia by 50% and 37.9 % respectively compared to the lowest incidence of candidiasis in the age group under 17 years old in female and male 8.8% and 13.5%, respectively. While the age group between 5-8 years was high, reaching 18 cases of oral candidiasis and 42% of children with leukemia compared with the age group, which was the least, that reached 9 cases, 21%. The highest incidence of was 59 isolates of females and males with leukemia, while was the least which was one isolate. was the most isolated from children with leukemia 13 isolates and was two isolates. showed the highest biofilm formation, 48 isolates were distributed between 21 strong and 27 weak biofilm production. The least biofilm formation isolates were , which reached six isolates and distributed between four strong and two isolates weak.

© 2020 [Author(s)], licensee HBKU Press.
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2020-11-15
2024-12-26
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/content/journals/10.5339/ajsr.2020.10
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عزل وتوصيف خميرة (Candida glabrata) من عينات سريرية في بعض مستشفيات مدينة بغداد
​​​​Arabian Journal of Scientific Research-المجلة العربية للبحث العلمي 1 (2020), 10 (2020); https://doi.org/10.5339/ajsr.2020.10
/content/journals/10.5339/ajsr.2020.10
/content/journals/10.5339/ajsr.2020.10
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  • Article Type: Research Article
Keyword(s): Candidemia, leukemia, biofilm formation, Baghdad hospitals. and مبيضات الدم، سرطان الدم، تشكيل الغشاء الحيوي، مستشفيات مدينة بغداد.

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