1887
Volume 2010, Issue 1
  • E-ISSN: 2220-2749

ملخص

Abstract

Although results from prior publications have indicated that normative bone mineral density (BMD) in Saudi Arabian women is significantly lower than their North American and European counterparts, there has been no systematic attempt to study these differences across the age-spectrum.

To explore these issues in more detail, a new Saudi Arabian normative BMD dataset was systematically derived from patient data at King Faisal Specialist Hospital & Research Centre in Riyadh. Changes in mean BMD were studied with respect to both age and years-since-menopause.

A retrospective analysis of BMD was carried out among 858 Saudi Arabian women who had undergone routine dual-energy x-ray absorptiometry. In addition to the usual patient details collected at each scan, information from questionnaires summarizing the patient’s medical, lifestyle and menopause history was also used to identify a subset of 179 presumed-normal women.

The normative BMD results for the L2-L4 AP-spine scans agree very closely with published data describing Jeddah women and indicate that during their postmenopausal years, the BMD of an average Saudi Arabian woman drops from a premenopausal plateau (i.e. peak bone mass) of 1.14 g cm−2, to a residual postmenopausal plateau of 0.92 g cm−2. The time-constant for this loss is 4.64 years.

We conclude that the average BMD of normal Saudi Arabian women is approximately 0.1 g cm−2 lower than European women across the entire adult age-range, but that the extent and rate of postmenopausal bone loss appears to lie within the normal European range. This suggests that osteoporosis is first manifested in young adults.

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References

  1. El-Desouki M. , (1995). Bone mineral density of the spine and femur in the normal Saudi population. Saudi Medical Journal. 16:, 1, 3035.
    [Google الباحث العلمي]
  2. Ghannam N.N., Hammami M.M., Bakheet S.M. and Khan B.A. , (1999). Bone mineral density of the spine and femur in healthy Saudi females: relation to vitamin D status, pregnancy, and lactation. Calcified Tissue International. 65:, 1, 2328.
    [Google الباحث العلمي]
  3. Ardawi M.S., Maimany A.A., Bahksh T.M., Nasrat H.A., Milaat W.A. and Al-Raddadi R.M. , (2005). Bone mineral density of the spine and femur in healthy Saudis. Osteoporosis International. 16:, 1, 4355.
    [Google الباحث العلمي]
  4. El-Desouki M.I. , (1999). Osteoporosis in postmenopausal Saudi women using dual X-ray bone densitometry. Saudi Medical Journal. 20:, 4, 283286.
    [Google الباحث العلمي]
  5. El-Desouki M.I. , (2003). Osteoporosis in postmenopausal Saudi women using dual x-ray bone densitometry. Saudi Medical Journal. 24:, 9, 953956.
    [Google الباحث العلمي]
  6. Al-Maatouq M.A., El-Desouki M.I., Othman S.A., Mattar E.H., Babay Z.A. and Addar M. , (2004). Prevalence of osteoporosis among postmenopausal females with diabetes mellitus. Audi Medical Journal. 25:, 10, 14231427.
    [Google الباحث العلمي]
  7. Sadat-Ali M., Al-Habdan I.M., Al-Mulhim F.A. and El-Hassan A.Y. , (2004). Bone mineral density among postmenopausal Saudi women. Saudi Medical Journal. 25:, 11, 16231625.
    [Google الباحث العلمي]
  8. Sadat-Ali M., Al-Habdan I., Al-Mulhim A.A. and El-Hassan A.Y. , (2005). Effect of parity on bone mineral density among postmenopausal Saudi Arabian women. Saudi Medical Journal. 26:, 10, 15881590.
    [Google الباحث العلمي]
  9. Outif A.M., Hendi A.A., Al-Dihan A.A. and Al-Ghamdi S.S. , (2004). Bone mineral density. What normative data should we use to report Saudi female patients?. Saudi Medical Journal. 25:, 8, 10401045.
    [Google الباحث العلمي]
  10. WHO Technical Report Series 843: Assessment of fracture risk and its application to screening for postmenopausal osteoporosis. 1994. World Health Organization. Geneva.
  11. Ilich J.Z. and Kerstetter J.E. , (2000). Nutrition in bone health revisited: a story bejond calcium. J. Amer. Coll. Nutrition. 19:, 6, 715737.
    [Google الباحث العلمي]
  12. Sowers M., Randolph J., Shapiro B. and Jannausch M. , (1995). A prospective study of bone density and pregnancy after an extended period of lactation with bone loss. Obstetrics and Gynecology. 85:, 2, 285289.
    [Google الباحث العلمي]
  13. Dawson-Hughes , Heaney R.P., Holick M.F., Lips P., Meuier P.J. and Veith R. , (2005). Osteoporos Int.. 16:, 713716.
    [Google الباحث العلمي]
  14. Sedrani S.H., Elidrissy A.W. and El-Arabi K.M. , (1983). Sunlight and vitamin D status in normal Saudi subjects. Am. J. Clinical Nutr.. 38:, 129132.
    [Google الباحث العلمي]
  15. Islam M.Z., Akhtaruzzaman M. and Lamberg-Allardt C. , (2006). Hypovitaminosis D is common in both veiled and nonveiled Bangladeshi women. Asia Pas. J. Clin. Nutr.. 15:, 1, 8187.
    [Google الباحث العلمي]
  16. Mishal A.A. , (2001). Effects of different dress styles on vitamin D levels in healthy yough Jordanian women. Osteoporos Int.. 2:, 931935.
    [Google الباحث العلمي]
  17. Hashemipour S., Larijani B., Adibi H., Javadi E., Sedeghat M., Pajouhi M., Soltani A., Shafaei A.R., Hamidi Z., Fard A.R.K., Hossein-Nezhad A.H. and Booya F. , (2004). Vitamin D deficiency and causative factors in the population of Tehran. BMC Publica Health. 4:, 38710.1186/1471-2458-4-38
    [Google الباحث العلمي]
  18. Meddeb N., Sahli H., Chahed M., Abdelmoula J., Feki M., Salah H., Frini S., Kaabachi N., Belkahia Ch Mbazaa, Zouari B. and Sellami S. , (2005). Vitamin D dediciency in Tunisia. Osteoporos Int.. 16:, 180183.
    [Google الباحث العلمي]
  19. Guzel R., Kozanoglu E., Guler-Uysal F., Soyupak S. and Sarpel T. , (2001). Vitamin D status and bone mineral density of veiled and unveiled Turkish women. Journal of Women’s Health and Gender-Based Medicine. 10:, 8, 765770.
    [Google الباحث العلمي]
  20. Allalli F., El Aichaoui S., Saoud B., Maaroufi H., Abouqal R. and Hajjaj-Hassouni N. , (2006). The impact of clothing style on bone mineral density among postmenopausal women in Morocco: a case-control study. BMC Public Health. 6:, 135
    [Google الباحث العلمي]
  21. Ahmed A.I.H., Blake G.M., Rymer J.M. and Fogelman I. , (1997). Screening for osteopenia and osteoporosis: do the accepted normal ranges lead to overdiagnosis?. Osteoporosis Int.. 7:, 432438.
    [Google الباحث العلمي]
  22. Genant H.K., Grampp S., Gluer C.C., Faulkner K.G., Jergas M., Engelke K., Hagiwara S. and Van Kuijk C. , (1994). Universal standardisation for dual X-ray absorptiometry: patient and phantom cross-claibration results. J. Bone Miner. Res.. 9:, 10, 15031514.
    [Google الباحث العلمي]
  23. Shipman A.J., Guy G.W.C., Smith I., Ostlere S., Greer W. and Smith R. , (1999). Vertebral bone mineral density, content and area in 8,789 normal women aged 33-73 years who have never had hormone replacement therapy. Osteoporosis Int.. 9:, 420426.
    [Google الباحث العلمي]
  24. Greer W., Shipman A.J. and Smith R. , (2003). A multi-exponential model of postmenopausal decline in vertebral bone mineral density: a new approach to the BMD reference range. Journal of Clinical Densitometry. 6:, 2, 97108.
    [Google الباحث العلمي]
  25. Greer W., Sandridge A.L. and Chehabeddine R.S. , (2003). The frequency distribution of age at natural menopause among Saudi Arabian women. Maturitas. 46:, 4, 263272.
    [Google الباحث العلمي]
  26. Bererhi H., Constable A., Lindell S.E., Countino J. and Kharousi W. , (1994). A study of bone mineral density versus age in Omani women and a comparison with normal British women. Nuclear Medicine Communications. 15:, 99103.
    [Google الباحث العلمي]
  27. Dougherty G. and Al-Marzouk , (2001). Bone Density measured by dual-energy X-ray absorptiometry in healthy Kuwaiti women. Calcif Tissue Int.. 68:, 225229.
    [Google الباحث العلمي]
  28. Maalouf G., Salem S., Sandid M., Attalah P., Eid J., Saliba N., Nehme I. and Johnell O. , (2000). Bone mineral density of the Lebanese reference population. Osteoporos Int.. 11:, 756764.
    [Google الباحث العلمي]
  29. Manisah M., Ozaksoy D., Yilmaz E., Senocak O., Tatari H., Baran O. and Havitcioglu H. , (2003). Bone mineral density reference values in the normal female and male population of Izmir. Turkey. Eur. Radiol.. 13:, 157162.
    [Google الباحث العلمي]
  30. Hammoudeh, M. , Al-Khayarin, M. , Zirie, M. and Bener, A., Bone density measured by dual energy X-ray absorptiometry in Qatari women. 2005;52(3–4):319–327.
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  • نوع المستند: Research Article
الموضوعات الرئيسية Bone mineral densityOsteoporosis and Saudi Arabia

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