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oa Is there a role for genetic risk assessment in the treatment of dyslipidemia in primary and secondary prevention of coronary heart disease?
- Source: Global Cardiology Science and Practice, Volume 2015, Issue 2, يونيو ٢٠١٥, 19
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- ١٢ مارس ٢٠١٥
- ٣٠ أبريل ٢٠١٥
- ٢٣ يونيو ٢٠١٥
ملخص
Genetic variants have been associated with the risk of coronary heart disease (CHD). Mega et al studied the association of a genetic risk score based on 27 genetic variants with incidents of recurrent CHD, adjusting for traditional risk factors using data from a community based study and 4 randomized controlled trials of both primary and secondary prevention with statin therapy. When individuals were divided into low, intermediate and high genetic risk categories, a significant gradient in risk of incident and recurrent CHD was shown.
© 2015 Al Suwaidi, licensee Bloomsbury Qatar Foundation Journals.