- ISSN: 1999-7086
- E-ISSN: 1999-7094
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oa Association between red blood cell distribution width and mortality in COVID-19
- Source: Journal of Emergency Medicine, Trauma and Acute Care, Volume 2023, Issue 2, سبتمبر ٢٠٢٣, 16
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- ٠١ فبراير ٢٠٢٣
- ٢٢ مارس ٢٠٢٣
- ٠٢ يوليو ٢٠٢٣
ملخص
Objective: In this study, we consider the heterogeneity of the results on the prognostic role of red cell distribution width (RDW) in COVID-19, and this study aimed to determine the relationship between RDW and mortality in COVID-19 patients.
Methods: This descriptive-analytical cross-sectional study was conducted on hospitalized COVID-19 patients whose disease was confirmed by PCR test positivity. Demographic characteristics, underlying diseases, and laboratory tests were the study variables. Patient outcomes were defined as in-hospital mortalities. The level of the Red Blood Cell Distribution Width-corpuscular volume (RDW-CV) in complete blood count (CBC) on arrival and the second day of hospitalization of patients and other variables were recorded in the checklist. The in-hospital mortalities were designated as the outcomes of the study.
Results: In this study, 201 patients were included, and the in-hospital mortality was 28 (13.9%). The correlation between variables in predicting in-hospital mortality using univariate regression analysis showed that there is a significant relationship between triage level, chronic lung disease and age, oxygen saturation, lymphocytes, BUN, and Cr CRP with in-hospital mortality; however, this significant relationship with RDW values of the patients on arrival and the first day of the hospitalization as well as △RDW (RDW on arrival – the first-day RDW) was not observed. Finally, based on the multivariate logistic regression model, there was a significant relationship between the triage level, age, and oxygen saturation with in-hospital mortality.
Conclusion: In COVID-19 patients, factors such as triage level, age, and oxygen saturation can play a significant role in predicting in-hospital mortality. The role of RDW in determining the outcome of the disease is still unclear.
