- ISSN: 0253-8253
- E-ISSN: 2227-0426
-
oa Drug-Resistant Epilepsy in Children with Juvenile Huntington's Disease: A Challenging Case and Brief Review
- Source: Qatar Medical Journal, Volume 2020, Issue 1, مارس ٢٠٢٠, 18
-
- ١٣ نوفمبر ٢٠١٩
- ٢٧ يناير ٢٠٢٠
- ١٤ يوليو ٢٠٢٠
ملخص
Huntington's Disease (HD) is an autosomal dominant neurodegenerative disorder with a progressive decline in cognitive, motor, and psychological function. Chorea tends to be the most common associated movement disorder, although other variants of several abnormal movements are also seen. Adult-onset HD is the most common subtype. Juvenile Huntington's disease (JHD) accounts for 5%–10% of all HD cases and presents as a rapidly progressive disorder with a multitude of characteristics. We report on a 9-year-old male with JHD who presented with refractory epilepsy. His EEG findings, seizure type, and antiepileptic drug usage are discussed with a brief review of the currently available relevant literature. The currently reported case sheds light on antiepileptic drugs that proved effective in our patient and the importance of screening for JHD when a child presents with seizures that are difficult to control.
