oa The Tragedy of Translation: Epistemological and Ethical Challenges Pertaining to Bringing Stem Cells to the Clinic

There is a profound moral question at the heart of all translational research: who should go first in human trials when the risks are not possible to estimate, the trial highly observed, and the effects of failure far-reaching?

This paper aims to address this question by unveiling the epistemological problem at its core. Second, the paper will draw attention to some of the unresolvable ethical challenges underlying any type of translational research involving human beings.