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Qatar Foundation Annual Research Forum Volume 2013 Issue 1
- Conference date: 24-25 Nov 2013
- Location: Qatar National Convention Center (QNCC), Doha, Qatar
- Volume number: 2013
- Published: 20 November 2013
181 - 200 of 541 results
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Impact of a school-based shisha use prevention program in Qatar: A pilot study
More LessBackground: Shisha: a re-emerging type of tobacco use contains harmful substances. Around 21% of 7 to 9th Graders students (29%: boys and 15.4%: girls) smoke any forms of tobacco in Qatar (GYTS, 2007). The prevalence of shisha use at young ages is alarming and calls for immediate intervention. To date, and despite the increasing prevalence of shisha use among youth, and its documented health hazards, no interven Read More
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Regional Differences In The Association Between Hiv And Hsv-2 Prevalence: Implications For Hiv Epidemic Potential
More LessABSTRACT Background and Objective HIV and herpes simplex virus type-2 (HSV-2) are sexually transmitted infections, with HSV-2 being nearly 10 times as infectious as HIV. HSV-2 prevalence has been established as an objective biomarker and a proxy measure of sexual risk behavior. HIV epidemics appear to be emerging in the Middle East and North Africa (MENA) region, but the time course and future size of these epide Read More
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Prevalence of vitamin D insufficiency in Qatar
By Alaa BadawiQatar has a high burden of chronic diseases including obesity, cardiovascular disease and type 2 diabetes mellitus. Low serum vitamin D levels have been implicated in the development and progression of a range of these chronic conditions. The prevalence of vitamin D insufficiency or deficiency in the general population of Qatar has still not been investigated. The aim of this study was to carry out a systematic review o Read More
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Health-related quality of life in midlife women in Qatar and the effect of arthritis
By Linda GerberHealth-related quality of life (HRQoL) measures are important indicators of perceived physical and mental health and are affected by changes in health status, demographic characteristics, culture, and ethnicity. Although recent studies have reported on HRQoL in midlife women in the US, most notably the Study of Women's Health Across the Nation (SWAN), there has been little research conducted on quality of life issues e Read More
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Benign paroxysmal positional vertigo: Early diagnosis and treatment by physical maneuver in the emergency department
By Furqan IrfanBenign paroxysmal positional vertigo is the most common form of vertigo seen in emergency departments. Typically these patients complain of the room spinning associated with certain head movements, nausea and vomiting. This condition can be diagnosed by taking a good history and performing a Dix-Hallpike manoeuvre. BPPV can be successfully treated by physical manoeuvres such as Epley, modified Epley, Semont Read More
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Three-Dimensional Structure Of The Human Cardiac Myosin Thick Filament - Clinical Implications
More LessAll muscles involve the interaction between two sets of filamentous proteins, actin and myosin, that leads to muscle contraction and force production mediated by the hydrolysis of ATP (Adenosine triphosphate). Actin filament structure is understood to high resolution, but myosin filament structure is much less well defined. The myosin filaments are formed from complicated arrangements of myosin molecules an Read More
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Controlling The Breast Cancer In Woman Of The World: Reducing Aggressive Surgeries, Radiation Exposure And Chemo Treatments
More LessThe most occurring cancer among women in the world is the breast cancer. It is still unknown what are the reasons one woman develops the breast cancer and another does not develop it. Advances in diagnostics and treatment options, increased understanding of breast cancer types, and, most recently, exploration in the role of genetic mutations in cancer development all have contributed to the reduction of fatalities. Read More
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Classification of newborn EEG signals using adaptive time-frequency distributions
By Nabeel KhanBackground: EEG signal are widely used for detecting abnormalities such as seizures in newborn babies. EEG signals have non-stationary characteristic, therefore time frequency distributions (TFDs) are a preferred tool for their analysis. The classification performance of most time-frequency (t-f) methods is restricted by the resolution limitation of TFDs. Objective: The main objective of this research is to propose a n Read More
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Hallmarks of regenerative medicine: Improved methods For reprogramming human fibroblasts using fluorescence activated cell sorting
More LessCurrent methods to derive induced pluripotent stem cell (iPSC) lines from human dermal fibroblasts by viral infection rely on complex protocols. One major factor contributing to the time required to derive lines is the ability of researchers to identify fully reprogrammed unique candidate clones from a mixed cell population containing transformed or partially reprogrammed cells and fibroblasts at an early time point post i Read More
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Akt-activated endothelium constitute the niche for residual disease and resistance to bevacizumab in ovarian cancer
More LessBackground. Ovarian cancer is the second leading cause of cancer-related death in women worldwide. Despite optimal cytoreduction and adequate adjuvant therapy, initial tumor response is often followed by relapse. Targeted therapies have been evaluated in ovarian cancer to overcome resistant disease. Among them anti-angiogenic therapies inhibit new blood vessel growth, induce endothelial cell apoptosis, and block th Read More
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Metabolomics profiling of dates subtypes
More LessDates form an important product of Qatari agriculture and further constitute an icon of the identity and heritage of the Arab world. Along many Arab countries, Qatar is engaging active research into studying the biology of dates with the view of improving the quality of the fruit both for commercial reasons as well as impact on the human health. As part of a major initiative of date biology research project at WCMC-Q, w Read More
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Diabetes And Colorectal Cancer: Could Ampk Signaling Pathway Explains The Link?
By Assaad EidBoth diabetes and cancer are prevalent diseases whose incidence is increasing worldwide and especially in countries that are undergoing rapid industrialization (i.e. Golf Countries). Lifestyle risk factors including diet, physical activity and obesity play a pivotal role in the etiology of both diseases. Epidemiological studies provide strong evidence that subjects with diabetes are at significantly higher risk of developing many Read More
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Characterization Of The Cellular, Biofilm And Pathogenic Properties Of Candida And Trichosporon Patient Samples Isolated At Hamad Medical Corporation
More LessDeep tissue fungal infections cause over 30% mortality and add over $2.6 billion to healthcare costs in the United States alone [1,2]. In Qatar, fungal infections occur in up to 16% of all patience's suffering from continuous ambulatory peritoneal dialysis [3]. Implanted medical devices such as artificial joints, catheters and artificial heart valves are associated with elevated rates of fungal bloodstream infections. One of the pr Read More
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Apoptosis resistance in prostate cancer cells and cancer stem cells: Implications of pro- and anti-apoptotic molecules in neuroendocrine differentiation
More LessProstate cancer (PC) is the second leading cause of cancer related death in men in several countries and is the most common cancer in men in Qatar according to recent statistics of the years 2010 and 2011. Understanding the molecular mechanisms underlying the development of PC progression is critical for developing novel therapies. Neuroendocrine (NE) differentiation of PC cells is an oncogenic process that has be Read More
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What type of exercise for metabolic syndrome?
More LessThe metabolic syndrome is a clustered syndrome characterized by five major abnormalities: cardiovascular risk factors, including elevated blood pressure, dyslipidemia, impaired glycemic control, and abdominal obesity. Although, this syndrome is reaching an epidemic spread in parallel to obesity, the incidence of the metabolic syndrome is expected to continue to rise, enabling the exercise prescription to contribute to opti Read More
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Investigating the drivers of the hepatitis C virus epidemic in Egypt
More LessBackground: Egypt has by far the highest national-level hepatitis C virus (HCV) prevalence in the world, with more than 14% of the general population infected with the virus. The drivers of such epidemic are still not completely identified, with previous parenteral antischistosomal therapy (PAT) campaigns conducted throughout Egypt proposed as the major contributor of the high HCV prevalence. In an effort to clarify speci Read More
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Human islets-clusters express coxsackie-adenovirus and decay accelerating receptors and reveals a distinctive microRNA disease-associated signature in T1D cellular models
More LessHuman Enterovirus (HEV) infections, speci?cally Coxsackievirus B(CVB), demonstrate ß-cell tropism and are associated with type 1 diabetes (T1D). Previous studies have shown that Coxsackie-Adenovirus receptors (CAR) and Decay Accelerating Factor (DAF) are both required to initiate CVB infection in human and rodent models, but this has not been examined in Human Islets-Clusters (HICS), which are derived from human i Read More
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Nebulized 5% or 3% hypertonic or 0.9% saline for treating acute bronchiolitis in infants
More LessAbstract Objective: To compare the efficacy and safety of 5%, 3%, and 0.9% saline solution for treating acute bronchiolitis in the prehospital setting. Study design: This was a double-blind trial including consecutive infants aged <18 months treated in an urban urgent care setting. A total of 165 patients were randomized to receive nebulized 5%, 3%, or 0.9% (normal) saline with epinephrine every 4 hours. The primary efficacy ou Read More
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The utilization of a U.S. Assessment, the Oregon project, on Arabic speaking pre-school students who are blind or visually impaired
By Hayat HejiOne reason why developmental delays and specific language disabilities are grossly under-identified outside of the U.S. is the absence of locally developed norm-referenced assessment tools for its multilingual and multicultural population (Ooi & Wong, 2012). As a result, there is a paucity of both quantitative and qualitative data on assessing developmental and language delays in different languages and cultural environment Read More
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Emerging role for colorectal cancer screening in Qatar
By Anil JohnIntroduction Colorectal cancer (CRC) is increasing in incidence in several Asian countries but screening programs are lacking. In Qatar, ,we embarked on a pilot study for Colo-Rectal Cancer (CRC) screening based at 3 primary health centers among subjects with average risk for colorectal cancer. Aim To devise a national screening program for the early detection of colonic cancer among persons at average risk f Read More
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