Qatar Foundation Annual Research Forum Volume 2013 Issue 1

Background: Individuals with diabetic peripheral neuropathy (DPN) frequently suffer from concomitant impaired proprioception and postural instability. Conventional exercise training has been demonstrated effective in improving balance; however these exercises are often repetitive, causing patients to lose interest and not complete the long term rehabilitation process. In addition, these programs do not incorporate v Read More

Endometriosis is a debilitating medical condition in females in which endometrial glands and stroma appear and flourish in areas outside the uterine cavity and walls, most commonly in the ovaries. Incidence in general population is 5-15% and around 30% in infertile women. Usual age group is 20-30years and patients present with dysmenorrhoea, dyspareunia, dyschezia, infertility and pelvic pain. We report two interesting case Read More

Type I interferon α/β (IFN-α/β) cytokines are produced by the host cell upon sensing viral proteins and nucleic acids as pathogen associated molecular patterns (PAMPs) and thereby elicit an antiviral response that represents the frontline of innate immunity against a virus infection. Among the signatures of the "non self" presence, double-stranded RNA (dsRNA) is the most potent PAMP in triggering the IFN-α/β-based Read More

Introduction: The objective of the "Italian Study on gene-environment interactions in lymphoma etiology", hereafter named the Italian GxE Study, is to identify individual conditions and external factors associated with lymphoma aetiology, the response to therapy and survival, as possible targets for preventive action and possible drivers of new individualized therapeutic strategies. Methods: This objective is being pursued by recrui Read More

الفكرة هي اعتبار عقل الطفل لا يوجد به البرنامج التشغيلي ي للعقل أو أن برنامج التشغيل الأولي لا يعمل كما يجب وهو فرضية أن عقل الطفل عندما يولد يكون عقله محمل ببرنامج مكتسب من الجينات وضعه الخالق سبحانه وتعالى نصه * انتبه إلى ما هو مكرر في بيئتك * انتبه إلى المثيرات البصرية التي تتكرر * انتبه إلى المثيرات السمعية التي تتكرر * سوف تتعرف على نفسك ومن حولك في حالة الطفل تم إهماله في الشهور الأولى مثل ترك الطفل ليشاهد قنوات الأطفال في أول 6 أشهر أو أن الدماغ لم يحفز فيصبح اقل ن Read More

Background & Objectives Aneurysm is a condition in which an abnormal dilation occurs in the wall of an artery or vein. Since cerebral aneurysm morphology is considered as a potential surrogate of rupture, clinicians often desire its segmentation before any pre-operative or interventional planning is performed. Also, segmentation of such images offers the potential of identifying the right treatment for a wide range of medi Read More

Spinal muscular atrophy (SMA) is an autosomal recessive disease affecting mainly the alpha motor neurons in the ventral horn of the spinal cord leading to muscular atrophy and paralysis. Although SMA is one of the leading genetic causes of infant mortality, no effective treatment is currently available. Gene delivery studies of Glial Derived Neurotrophic (GDNF) in Parkinson's disease (PD) have demonstrated positive impacts in Read More

Cancer develops as a result of a defective apoptotic system. Anticancer drugs mainly aim to modulate apoptosis. Multiple publications strongly support the link between the elevation of the intracellular calcium concentration and the induction of apoptosis. Cisplatin was one of the pioneers of the metal based anticancer drugs. Many tumors have been treated with cisplatin and other platin-based anti-cancer drugs like carboplat Read More

The computational advances in recent times have led to analysis of the complex interaction of blood flow through elastic artery. This aids in prognosing the progression and behaviour of cardiovascular diseases like atherosclerosis, aneurysms etc. In the present investigation, an idealistic 66% eccentric stenosed common carotid artery is analyzed under normal blood pressure condition based on clinical data obtained from Read More