1887
Volume 2022, Issue 4
  • ISSN: 1999-7086
  • E-ISSN: 1999-7094

ملخص

Although various scoring systems are already available for early prognostic evaluation of patients with complicated intra-abdominal infections (cIAIs), none has shown the ideal characteristics in everyday practice. In this study, we aimed to find the most reliable prognostic score in patients with cIAIs. This retrospective study involved 110 patients with cIAIs admitted to the Department of Surgical Diseases at University Hospital, “Prof. Dr. Stoyan Kirkovich” Stara Zagora from January 2017 to July 2019. We compared the prognostic values of Mannheim Peritonitis Index (MPI), World Society of Emergency Surgery Sepsis Severity Score (WSES SSS), quick sequential (sepsis-related) organ failure assessment score (qSOFA), and systemic inflammatory response syndrome (SIRS) using area under receiver operating characteristics (AUROC) curves. Bivariate correlation analysis was used to evaluate the association between scoring systems and the final outcome. The observed in-hospital mortality was 22.7%. Significant correlations were found between MPI and outcome ( = 0.500, <  0.001), WSES SSS and outcome ( = 0.483, <  0.001), and qSOFA and outcome ( = 0.356, <  0.001). Of all the scoring systems, MPI showed the best prognostic performance (AUROC = 0.844, 95% confidence interval (CI) = 0.763–0.924). The identified sensitivity and specificity for MPI cut-off value >25 points were 80% and 77.6%, respectively. The MPI is still one of the best options for prognostic evaluation of patients with cIAIs.

Loading

جارٍ تحميل قياسات المقالة...

/content/journals/10.5339/jemtac.2022.24
٢٠٢٢-٠٧-٢٢
٢٠٢٤-٠٧-١٢
Loading full text...

Full text loading...

/deliver/fulltext/jemtac/2022/4/jemtac.2022.24.html?itemId=/content/journals/10.5339/jemtac.2022.24&mimeType=html&fmt=ahah

References

  1. Menichetti F, Sganga G. Definition and classification of intra-abdominal infections. J Chemother. 2009 Jul; 21:(suppl 1):3–4.
    [Google الباحث العلمي]
  2. Vincent JL, Rello J, Marshall J, Silva E, Anzueto A, Martin CD, et al. International study of the prevalence and outcomes of infection in intensive care units. JAMA. 2009; 302:(21):2323–9.
    [Google الباحث العلمي]
  3. Wacha H, Linder MM, Feldman U, Wesch G, Gundlach E, Steifensand RA. Mannheim peritonitis index (prediction of risk of death from peritonitis: construction of a statistical and validation of an empirically based index. Theoretical Surg. 1987;1:169–77.
    [Google الباحث العلمي]
  4. Qureshi AM, Zafar A, Saeed K, Quddus A. Predictive power of Mannheim Peritonitis Index. J Coll Physicians Surg Pak. 2005 Nov; 15:(11):693–6.
    [Google الباحث العلمي]
  5. Budzyński P, Dworak J, Natkaniec M, Pędziwiatr M, Major P, Migaczewski M, et al. The usefulness of the Mannheim Peritonitis index score in assessing the condition of patients treated for peritonitis. Pol Przegl Chir. 2015 Jun; 87:(6):301–6. doi: 10.1515/pjs-2015-0058..
    [Google الباحث العلمي]
  6. Sartelli M, Catena F, Ansaloni L, Coccolini F, Corbella D, Moore EE, et al. Complicated intra-abdominal infections worldwide: the definitive data of the CIAOW Study. World J Emerg Surg. 2014 May; 14:(9):37.
    [Google الباحث العلمي]
  7. Sartelli M, Abu-Zidan FM, Catena F, Griffiths EA, Di Saverio S, Coimbra R, et al. Global validation of the WSES Sepsis Severity Score for patients with complicated intra-abdominal infections: a prospective multicentre study (WISS Study). World J Emerg Surg. 2015Dec; 16:(10):61.
    [Google الباحث العلمي]
  8. Mwenda KI, Ojuka D, Awori M. Utility of World Society of Emergency Surgery Sepsis Severity Score in predicting outcomes of intra-abdominal infections. Ann Afr Surg. 2020May; 17:(2):65–8.
    [Google الباحث العلمي]
  9. Godínez-Vidal AR, Vázquez-Rentería R, Guerrero-Ponce AE, et al. Use of the WSES scale to predict mortality in patients with intra-abdominal infection. Rev Mex de Cirugía del Aparato Digestivo. 2020; 9:(2):65–70.
    [Google الباحث العلمي]
  10. Bone RC, Balk RA, Cerra FB, Dellinger RP, Fein AM, Knaus WA, et al. Definitions for sepsis and organ failure and guidelines for the use of innovative therapies in sepsis. Chest. 1992Jun; 101:(6):1644–55.
    [Google الباحث العلمي]
  11. Singer M, Deutschman CS, Seymour CW, Shankar-Hari M, Annane D, Bauer M, et al. The third international consensus definitions for sepsis and septic shock (Sepsis-3). JAMA. 2016Feb; 315:(8):801–10. doi: 10.1001/jama.2016.0287..
    [Google الباحث العلمي]
  12. Freund Y, Lemachatti N, Krastinova E, Van Laer M, Claessens Y-E, Avondo A, et al. Prognostic accuracy of Sepsis-3 criteria for in-hospital mortality among patients with suspected infection presenting to the emergency department. JAMA. 2017Jan; 317:(3):301–8.
    [Google الباحث العلمي]
  13. Osatnik J, Tort-Oribea B, Folco J, et al. Predictive performance of Quick Sequential Organ Failure Assessment Scoring in an Argentinian hospital. J Clin Diagnostic Res. 2018Oct; 12:(10):22–6.
    [Google الباحث العلمي]
  14. Goulden R, Hoyle M-C, Monis J, et al. qSOFA, SIRS and NEWS for predicting inhospital mortality and ICU admission in emergency admissions treated as sepsis. Emerg Med J. 2018Jun; 35:(6):345–9.
    [Google الباحث العلمي]
  15. Jung YT, Jeon J, Park JY, Kim MJ, Lee SH, Lee JG. Addition of lactic acid levels improves the accuracy of quick sequential organ failure assessment in predicting mortality in surgical patients with complicated intra-abdominal infections: a retrospective study. World J Emerg Surg. 2018 Mar;13:14.
    [Google الباحث العلمي]
  16. Raimondo S, Sartelli M, Coccolini F, et al. Which prognostic score for abdominal sepsis? Analysis of final results of PIPAS (Physiological Indicators for Prognosis in Abdominal Sepsis) study in a single center. J Peritoneum (and other serosal surfaces). 2018;3:106.
    [Google الباحث العلمي]
  17. McLauchlan GJ, Anderson ID, Grant IS, Fearon KC. Outcome of patients with abdominal sepsis treated in an intensive care unit. Br J Surg. 1995;85:524–9.
    [Google الباحث العلمي]
  18. Bosscha K, Reijnders K, Hulstaert PF, Algra A, van der Werken C. Prognostic scoring systems to predict outcome in peritonitis and intra-abdominal sepsis. Br J Surg. 1997;84:1532–4.
    [Google الباحث العلمي]
  19. Ohmann C, Yang Q, Hau T, Wacha H. Prognostic modelling in peritonitis. Peritonitis Study Group of the Surgical Infection Society Europe. Eur J Surg. 1997;163:53–60.
    [Google الباحث العلمي]
  20. Raith EP, Udy AA, Bailey M, McGloughlin S, MacIsaac C, Bellomo R, Pilcher DV. Prognostic accuracy of the SOFA acore, SIRS criteria, and qSOFA score for in-hospital mortality among adults with suspected infection admitted to the intensive care unit. JAMA. 2017Jan; 317:(3):290–300. doi: 10.1001/jama.2016.20328..
    [Google الباحث العلمي]
  21. Tolonen M, Coccolini F, Ansaloni L, Sartelli M, Roberts DJ, McKee JL, et al. Getting the invite list right: a discussion of sepsis severity scoring systems in severe complicated intra-abdominal sepsis and randomized trial inclusion criteria. World J Emerg Surg. 2018 Apr;13:17. doi: 10.1186/s13017-018-0177-2..
    [Google الباحث العلمي]
  22. Sazhin A, Ivakhov G, Stradymov E, Petukhov V, Titkova S. The modified Boey score (mBoey) for outcome prediction in patients with perforated peptic ulcer complicated by diffuse peritonitis: a retrospective study. Research Square. 2020. DOI: 10.21203/rs.3.rs-28623/v1..
    [Google الباحث العلمي]
  23. Demmel N, Magg K, Osterholzer G. The value of clinical parameters for determining the prognosis of peritonitis validation of the Mannheim Peritonitis Index. Langenbecks Arch Chir. 1994; 379:(3):152–8.
    [Google الباحث العلمي]
  24. Billing A, Fröhlich D, Schildberg FW. Prediction of outcome using the Mannheim peritonitis index in 2003 patients. Peritonitis Study Group. Br J Surg. 1994Feb; 81:(2):209–13. doi: 10.1002/bjs.1800810217..
    [Google الباحث العلمي]
  25. Salamone G, Licari L, Falco N, Augello G, Tutino R, Campanella S, et al. Mannheim Peritonitis Index (MPI) and elderly population: prognostic evaluation in acute secondary peritonitis. G Chir. 2016 Nov-Dec; 37:(6):243–9.
    [Google الباحث العلمي]
  26. Neri A, Marrelli D, Scheiterle M, Di Mare G, Sforza S, Roviello F. Re-evaluation of Mannheim prognostic index in perforative peritonitis: prognostic role of advanced age. A prospective cohort study. Int J Surg. 2015 Jan;13:54–9.
    [Google الباحث العلمي]
  27. Koppad SN, Vandakudri AB, Desai M, Kodliwadmath H. Analysis of Mannheim peritonitis index scoring in predicting outcome in patients with peritonitis secondary to hollow viscous perforation. Int Surg J. 2016;3:1116–20.
    [Google الباحث العلمي]
/content/journals/10.5339/jemtac.2022.24
Loading
/content/journals/10.5339/jemtac.2022.24
Loading

جارٍ تحميل البيانات والوسائط...

  • نوع المستند: Research Article
الموضوعات الرئيسية intra-abdominal infectionsmortalityMPIoutcomeqSOFA and WSES SSS

الأكثر اقتباسًا لهذا الشهر Most Cited RSS feed

هذه الخانة مطلوبة
يُرجى إدخال عنوان بريد إلكتروني صالح
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error