1887
Volume 2010, Issue 2
  • ISSN: 0253-8253
  • E-ISSN: 2227-0426

ملخص

A 45 years old man reports recurrent episodes of marked lip and hand swelling; without urticaria or puritus occurring during surgical procedure for lymph nodes biopsy. He was diagnosed with lymphoma six months ago. He has had three episodes of severe, campy abdominal pain and bloating lasting up to 24–36 hours on the past year. No family history of Angioedema. Work up showed: CBC, chemistry and IgE were normal. C4 was 35 mg/dL (normal 50–100 mg/dl) C1 esterase inhibitor (C1 -INH) level: 18 mg/dL (normal 18–50 mg/dl), low C1 -INH function (less than 50% of normal) and low C1 q (less than 30% of normal)

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References

  1. Agostoni A, Aygoren-Pursun E, Binkley KE. Hereditary and acquired angioedema; problems and progress; proceedings of the third C 7 esterase inhibitor deficiency workshop and beyond. J Allergy Clin Immunol. 2004; 114::551.
    [Google الباحث العلمي]
  2. Bowen T, Cicardi M, Farkas H. Canadian 2003 International Consensus Algorithm For the Diagnosis, Therapy, and Management of Hereditary Angioedema. J Allergy Clin Immunol. 2004; 114::629.
    [Google الباحث العلمي]
  3. Weiler CR, Van Dellen RG. Genetic test indications and interpretations in patients with hereditary angioedema. Mayo Clin Proc. 2006; 81::958.
    [Google الباحث العلمي]
  4. Cicardi M, Zingale LC, Pappalardo E. Autoantibodies and lymphoproliferative diseases in'acquired C1-inhibitor deficiencies. Medicine (Baltimore). 2003; 82::274.
    [Google الباحث العلمي]
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  • نوع المستند: Research Article

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