1887
Volume 2021, Issue 3
  • ISSN: 0253-8253
  • E-ISSN: 2227-0426

ملخص

Introduction: Chronic pelvic pain (CPP) is a diagnostic and therapeutic challenge affecting women of all ages globally. The syndrome is not well understood, but the association of interstitial cystitis (IC) with endometriosis in causing CPP should not be overlooked in managing this cohort. Herein, we present a mini review of this association to evaluate the literature in determining the prevalence of endometriosis and IC concomitantly in patients with CPP, diagnostic limitations, and clinical implications.

Methods: A Medline search of the key words “evil twins’ syndrome,” “interstitial cystitis,” “bladder pain syndrome,” and “endometriosis” was conducted for full-text articles published in English over the past 20 years. The search yielded 40 articles, of which 21 were selected. Cross-referencing bibliographies of each publication yielded an additional 25 references.

Results: Both endometriosis and IC share a similar array of symptoms that are often exacerbated during the perimenstrual period. Multiple authors have reported the frequent coexistence of these two conditions. Over 80% of patients with CPP were found to have both conditions. The prevalence of endometriosis and IC coexistence was greater than that of each condition separately.

Conclusions: It is crucial to look beyond the traditionally diagnosed endometriosis as the cause of CPP. This is true especially in patients whose previous treatment was ineffective. Simultaneous assessment for both conditions is essential to avoid the frequently delayed diagnosis and prevent unsuccessful medical and surgical therapies.

Loading

جارٍ تحميل قياسات المقالة...

/content/journals/10.5339/qmj.2021.50
٢٠٢١-١٠-٠٧
٢٠٢٤-٠٧-١١
Loading full text...

Full text loading...

/deliver/fulltext/qmj/2021/3/qmj.2021.50.html?itemId=/content/journals/10.5339/qmj.2021.50&mimeType=html&fmt=ahah

References

  1. Mathias SD, Kuppermann M, Liberman RF, Lipschutz RC, Steege JF (1999) Chronic pelvic pain: prevalence, health-related quality of life, and economic correlates. Obstet Gynecol 87:321–327. doi: 10.1016/0029-7844(95)00458-0 .
    [Google الباحث العلمي]
  2. Latthe P, Latthe M, Say L, Khan KS (2006) WHO systematic review of prevalence of chronic pelvic pain: Neglected reproductive health morbidity. BMC Public Health 6:177. doi: 10.1186/1471-2458-6-177 .
    [Google الباحث العلمي]
  3. Chung MK, Chung RR, Gordon D, Jennings C (2002) The evil twins of chronic pelvic pain syndrome: endometriosis and interstitial cystitis. JSLS 6:(4):311–4.
    [Google الباحث العلمي]
  4. Paulson JD, Paulson JN (2011) Anterior vaginal wall tenderness (AVWT) as a physical symptom in chronic pelvic pain. JSLS 15:(1):6–9. doi: 10.4293/108680810X12924466008961 .
    [Google الباحث العلمي]
  5. Stanford EJ, Dell JR, Parsons CL (2007) The emerging presence of interstitial cystitis in gynecologic patients with chronic pelvic pain. Urology 69:(4):53–9.
    [Google الباحث العلمي]
  6. Ahangari A (2014) Prevalence of chronic pelvic pain among women: An updated review. Pain Physician 17:E141–E147.
    [Google الباحث العلمي]
  7. Chen I, Thavorn K, Shen M, Goddard Y, Yong P, MacRae GS, et al. (2017) Hospital-associated costs of chronic pelvic pain in Canada: A population-based descriptive study. J Obstet Gynaecol Can 39:(3):174–180. doi: 10.1016/j.jogc.2016.12.008. .
    [Google الباحث العلمي]
  8. Stanford EJ, Koziol J, Feng A (2005) The prevalence of interstitial cystitis, endometriosis, adhesions, and vulvar pain in women with chronic pelvic pain. J Minim Invasive Gynecol 12:(1):43–9.
    [Google الباحث العلمي]
  9. Bogart LM, Berry SH, Clemens JQ (2007) Symptoms of interstitial cystitis, painful bladder syndrome and similar diseases in women: A systematic review. J Urol 177:(2):450–6. doi: 10.1016/j.juro.2006.09.032 .
    [Google الباحث العلمي]
  10. Cheng C, Rosamilia A, Healey M (2012) Diagnosis of interstitial cystitis/ bladder pain syndrome in women with chronic pelvic pain: A prospective observational study. Int Urogynecol J 23:(10):1361–6. doi: 10.1007/s00192-012-1711-5 .
    [Google الباحث العلمي]
  11. Bogart LM, Suttorp MJ, Elliot MN, Clemens JQ, Berry SH (2011) Prevalence and correlates of sexual dysfunction among women with bladder pain syndrome/ interstitial cystitis. Urology 77:(3):576–80. doi: 10.1016/j.urology.2010.10.016 .
    [Google الباحث العلمي]
  12. Butrick CW (2003) Interstitial cystitis and chronic pelvic pain: New insights in neuropathology, diagnosis, and treatment. Clin Obstet Gynecol 46:(4):811–23. doi: 10.1097/00003081-200312000-00011 .
    [Google الباحث العلمي]
  13. Rackow BW, Novi JM, Arya LA, Pfeifer SM (2009) Interstitial cystitis is an etiology of chronic pelvic pain in young women. J Pediatr Adolesc Gynecol 22:(3):181–5. http://dx.doi.org/10.1016/j.jpag.2008.04.008 .
    [Google الباحث العلمي]
  14. Dell JR, Mokrzycki ML, Jayne CJ (2009) Differentiating Interstitial Cystitis from similar conditions commonly seen in gynecologic practice. Eur J Obstet Gynecol Reprod Biol 144:(2):105–9. doi: 10.1016/j.ejogrb.2009.02.050 .
    [Google الباحث العلمي]
  15. Chung MK, Chung RP, Gordon D (2005) Interstitial Cystitis and Endometriosis in patients with chronic pelvic pain: The “Evil Twins” Syndrome. JSLS 9:(1):25–29.
    [Google الباحث العلمي]
  16. Lessey BA, Savaris RF, Ali S, Brophy S, Tomazic-Allen S, Chwalisz K (2015) Diagnostic accuracy of urinary cytokeratin 19 fragment for endometriosis. Reprod Sci 22:(5):551–5. doi: 10.1177/1933719114553064 .
    [Google الباحث العلمي]
  17. Denny E, Mann CH (2007) Endometriosis-associated dyspareunia: The impact on women's lives. J Fam Plann Reprod Health Care 33:(3):189–93. doi: 10.1783/147118907781004831 .
    [Google الباحث العلمي]
  18. Yong PJ, Sadownik L, Brotto LA (2015) Concurrent deep-superficial dyspareunia: Prevalence, associations, and outcomes in a multidisciplinary vulvodynia program. J Sex Med 12:(1):219–27. doi: 10.1111/jsm.12729 .
    [Google الباحث العلمي]
  19. Butrick CW (2007) Patients with chronic pelvic pain: endometriosis or interstitial cystitis/painful bladder syndrome? JSLS 11:(2):182–9.
    [Google الباحث العلمي]
  20. Smorgick N, Marsh CA, As-Sanie S, Smith YR, Quint EH (2013) Prevalence of pain syndromes, mood conditions, and asthma in adolescents and young women with endometriosis. J Pediatr Adolesc Gynecol 26:(3):171–5. doi: 10.1016/j.jpag.2012.12.006 .
    [Google الباحث العلمي]
  21. Paulson JD, Delgado M (2007) The relationship between interstitial cystitis and endometriosis in patients with chronic pelvic pain. JSLS 11:(2):175–81.
    [Google الباحث العلمي]
  22. Chung MK (2004) Interstitial cystitis in persistent posthysterectomy chronic pelvic pain. JSLS 8:(4):329–33.
    [Google الباحث العلمي]
  23. Langenberg PW, Wallach EE, Clauw DJ, Howard FM, Diggs CM, Wesselmann U, et al. (2010) Pelvic pain and surgeries in women before interstitial cystitis/painful bladder syndrome. Am J Obstet Gynecol 202:(3):286.e1–6. doi: 10.1016/j.ajog.2009.10.866 .
    [Google الباحث العلمي]
  24. Warren JW, Wesselmann U, Morozov V, Langenberg PW (2011) Numbers and types of nonbladder syndromes as risk factors for interstitial cystits/painful bladder syndrome. Urology 77:(2):313–9. doi: 10.1016/j.urology.2010.08.059 .
    [Google الباحث العلمي]
  25. Warren JW, Howard FM, Cross RK, Good JL, Weissman MM, Wesselmann U, et al (2009) Antecedent nonbladder syndromes in case-control study of interstitial cystitis/painful bladder syndrome. Urology 73:(1):52–7. doi: 10.1016/j.urology.2008.06.031 .
    [Google الباحث العلمي]
  26. Ingber MS, Peters KM, Killinger CA, Carrico DJ, Ibrahim IA, Diokno AC (2008) Dilemmas in diagnosing pelvic pain: multiple pelvic surgeries in women with interstitial cystitis. Int Urogynecol J Pelvic Floor Dysfunct 19:(3):341–5. doi: 10.1007/s00192-007-0453-2 .
    [Google الباحث العلمي]
  27. Powell-Boone T, Ness TJ, Cannon R, Lloyd LK, Weigent DA. Fillingim RB (2005) Menstrual cycle affects bladder pain sensation in subjects with interstitial cystitis. J Urol 174:(5):1832–6. 10.1097/01.ju.0000176747.40242.3d .
    [Google الباحث العلمي]
  28. Ferrero S, Ragni N, Remorgida V (2008) Deep dyspareunia: causes, treatments, and results. Curr Opin Obstet Gynecol 20:(4):394–9. doi: 10.1097/GCO.0b013e328305b9ca .
    [Google الباحث العلمي]
  29. Kahn BS, Tatro C, Parsons CL, Willems JJ (2010) Prevalence of interstitial cystitis in vulvodynia patients detected by bladder potassium sensitivity. J Sex Med 7:(2 Pt 2):996–1002. doi: 10.1111/j.1743-6109.2009.01550.x .
    [Google الباحث العلمي]
  30. Gardella B, Porru D, Nappi RE, Daccò MD, Chiesa A, Spinillo A (2011) Interstitial cystitis is associated with vulvodynia and sexual dysfunction- a case-control study. J Sex Med 8:(6):1726–34. doi: 10.1111/j.1743-6109.2011.02251.x .
    [Google الباحث العلمي]
  31. Parsons CL (2011) The role of a leaky epithelium and potassium in the generation of bladder symptoms in interstitial cystitis/overactive bladder, urethral syndrome, prostatitis and gynaecological chronic pelvic pain. BJU Int 107:(3):370–5. doi: 10.1111/j.1464-410X.2010.09843.x .
    [Google الباحث العلمي]
  32. Parsons CL, Dell J, Stanford EJ, Bullen M, Kahn BS, Waxell T, et al. (2002) Increased prevalence of interstitial cystitis: previously unrecognized urologic and gynecologic cases identified using a new symptom questionnaire and intravesical potassium sensitivity. Urology 60:(4):573–8. doi: 10.1016/S0090-4295(02)01829-0 .
    [Google الباحث العلمي]
  33. Gardella B, Porru D, Ferdeghini F, Martinotti Gabellotti E, Nappi RE, Rovereto B, et al. (2008) Insight into urogynecologic features of women with interstitial cystitis/ painful Bladder syndrome. Eur Urol 54:(5):1145–51. doi: 10.1016/j.eururo.2008.01.079 .
    [Google الباحث العلمي]
  34. Hurd WW (1998) Criteria that indicate endometriosis is the cause of chronic pelvic pain. Obstet Gynecol 92:(6):1029–32.
    [Google الباحث العلمي]
  35. Gillenwater JY, Wein AJ. Summary of the National Institute of Arthritis, Diabetes, Digestive and Kidney Diseases Workshop on Interstitial Cystitis, National Institutes of Health, Bethesda, Maryland, August 28–29, 1987. J Urol. 1988 Jul; 140:(1):203–6.
  36. Nordling J, Anjum FH, Bade JJ, Bouchelouche K, Bouchelouche P, Cervigni M, et al. (2004) Primary evaluation of patients suspected of having Interstitial Cystitis. Eur Urol 45:(5):662–9. doi: 10.1016/j.eururo.2003.11.021 .
    [Google الباحث العلمي]
  37. van de Merwe J, Nordling J, Bouchelouche P, Bouchelouche K, Cervigni M, Daha LK, et al. (2008) Diagnostic criteria, classification, and nomenclature for Painful Bladder Syndrome/ Interstitial Cystitis: An ESSIC proposal. Eur Urol 53:(1):60–7. Epub 2007 Sep 20. doi: 10.1016/j.eururo.2007.09.01956 .
    [Google الباحث العلمي]
  38. Berry SH, Bogart LM, Pham C, Liu K, Nyberg L, Stoto M, et al. (2010) Development, validation, and testing of an epidemiological case definition of interstitial cystitis/ painful bladder syndrome. J Urol 183:(5):1848–52. doi: 10.1016/j.juro.2009.12.103 .
    [Google الباحث العلمي]
/content/journals/10.5339/qmj.2021.50
Loading
/content/journals/10.5339/qmj.2021.50
Loading

جارٍ تحميل البيانات والوسائط...

الأكثر اقتباسًا لهذا الشهر Most Cited RSS feed

هذه الخانة مطلوبة
يُرجى إدخال عنوان بريد إلكتروني صالح
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error